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Links from GEO DataSets

Items: 11

1.

Global Transcriptome Analysis of Tropheryma whipplei in Response to Temperature Stresses

(Submitter supplied) Microarray analysis of the global gene expression patterns of Tropheryma whipplei in response to thermal stresses showed unique transcription profiles. A few genes were regulated after 15 min exposure at 43°C, including the dnaK regulon composed of grpE, hspR, dnaK, clpB, cbpA as well as the TWT745 ORFan gene which might encode for another heat-shock protein. This operon is likely to be regulated by two HspR associated inverted repeats (HAIR motifs) found within its 5' region. more...
Organism:
Tropheryma whipplei
Type:
Expression profiling by array
Platform:
GPL3210
12 Samples
Download data
Series
Accession:
GSE3693
ID:
200003693
2.

Transcriptome analysis of Shewanella oneidensis MR-1 in response to cold shock

(Submitter supplied) This study presents a global transcriptional analysis of the cold shock response of Shewanella oneidensis MR-1 after a temperature downshift from 30 to 8 or 15oC based on time-series microarray experiments. More than 700 genes were found to be significantly affected (p < 0.05) upon cold shock challenge, especially at 8oC. The temporal gene expression patterns of the classical cold-shock genes varied and only some of them, most notably so1648 and so2787, were differentially regulated in response to temperature downshift. more...
Organism:
Shewanella oneidensis MR-1
Type:
Expression profiling by array
Platform:
GPL3253
60 Samples
Download data
Series
Accession:
GSE4489
ID:
200004489
3.

Molecular Basis of Tropheryma whipplei Doxycycline Susceptibility Examined by Transcriptional Profiling

(Submitter supplied) The suceptibility of T. whipplei to doxycycline was investigated at the transcriptional level using a whole-genome DNA microarray. The microarray data showed good agreement with real-time quantitative PCR (R = 0.969). Exposure of T. whipplei with the subinhibitory concentration of doxycycline allowed to observe antibiotic-specific primary expression profiles, while indirect effects were detected with a 10 times higher concencentration. more...
Organism:
Tropheryma whipplei
Type:
Expression profiling by array
Platform:
GPL3210
9 Samples
Download data: TXT
Series
Accession:
GSE5717
ID:
200005717
4.

Transcriptome analysis of Escherichia coli O157:H7 EDL933 during heat shock using microarrays

(Submitter supplied) The transcriptome of Escherichia coli K-12 has been widely studied over a variety of conditions for the past decade while such studies involving E. coli O157:H7, its pathogenic cousin, are just now being conducted. To better understand the impact of heat shock on E. coli O157:H7, global transcript levels of strain EDL933 cells shifted from 37°C to 50°C for 15 min were compared to cells left at 37°C using microarrays. more...
Organism:
Escherichia coli; Escherichia coli O157:H7 str. EDL933
Type:
Expression profiling by array
Platform:
GPL6272
12 Samples
Download data: TXT
Series
Accession:
GSE11463
ID:
200011463
5.

Expression data from brain tissue of Rattus norvegicus treated with D-Serine

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3643
Platform:
GPL1355
24 Samples
Download data: CEL
Series
Accession:
GSE10748
ID:
200010748
6.
Full record GDS3643

D-serine effect on the brain: dose response

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 6 dose sets
Platform:
GPL1355
Series:
GSE10748
24 Samples
Download data: CEL
DataSet
Accession:
GDS3643
ID:
3643
7.

The black truffle of Perigord responds to a temperature shift with an extensive reprogramming of its transcriptional activity

(Submitter supplied) Taking advantage of the availability of the Tuber melanosporum genome sequence and a whole-genome microarray, we wanted to test the hypothesis that the transition from a growth temperature of 24-25°C to a cold one (4°C) is perceived by the filamentous fungus at the transcriptomic level and we wanted to identify and characterize the genes involved in this stress response.
Organism:
Tuber melanosporum
Type:
Expression profiling by array
Platform:
GPL8982
6 Samples
Download data: PAIR, TXT
Series
Accession:
GSE21626
ID:
200021626
8.

Shewanella piezotolerans WP3 wild-type strain under heat shock

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Shewanella piezotolerans WP3
Type:
Expression profiling by array
Platform:
GPL16568
18 Samples
Download data
Series
Accession:
GSE82264
ID:
200082264
9.

Comparative genomic analysis of T.whipplei strains reveals that diversity is mainly related to the WiSP proteins

(Submitter supplied) In this work we analyzed the genomic diversity of several Tropheryma whipplei strains by microarray based-comparative genomic hybridization. Fifteen clinical isolates originating from biopsy samples recovered from different countries were compared with the T. whipplei Twist strain. For each isolate, the genes were defined as either present or absent/divergent using the GACK analysis software. Genomic changes were then further characterized by PCR and sequencing. more...
Organism:
Tropheryma whipplei
Type:
Genome variation profiling by array
Platform:
GPL3210
48 Samples
Download data: TXT
Series
Accession:
GSE7453
ID:
200007453
10.

Shewanella piezotolerans WP3 wild-type strain under high hydrostatic pressure

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Shewanella piezotolerans WP3
Type:
Expression profiling by array
Platform:
GPL16568
12 Samples
Download data: GPR
Series
Accession:
GSE82267
ID:
200082267
11.

Shewanella piezotolerans WP3 wild-type strain under cold shock

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Shewanella piezotolerans WP3
Type:
Expression profiling by array
Platform:
GPL16568
18 Samples
Download data
Series
Accession:
GSE82259
ID:
200082259
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