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Links from GEO DataSets

Items: 1 to 20 of 23

1.
Full record GDS3009

Hedgehog-induced medulloblastoma model (MG-430B)

Analysis of medulloblastoma tumors formed in transgenics by expressing an activated form of Smoothened (Smo). Expression of the activated Smo transmembrane protein results in activation of Hh signaling. Results provide insight into the molecular mechanisms underlying Hh-related tumorigenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL340
Series:
GSE9299
5 Samples
Download data: CEL
DataSet
Accession:
GDS3009
ID:
3009
2.
Full record GDS3008

Hedgehog-induced medulloblastoma model (MG-430A)

Analysis of medulloblastoma tumors formed in transgenics by expressing an activated form of Smoothened (Smo). Expression of the activated Smo transmembrane protein results in activation of Hh signaling. Results provide insight into the molecular mechanisms underlying Hh-related tumorigenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL339
Series:
GSE9299
5 Samples
Download data: CEL
DataSet
Accession:
GDS3008
ID:
3008
3.
Full record GDS2906

Embryonic stem cells and embryoid bodies (MG-430B)

Comparison of J1 embyronic stem cells and J1 embryoid bodies. Results provide insight into the molecular mechanisms responsible for maintaining the embryonic stem cell phenotype.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 development stage sets
Platform:
GPL340
Series:
GSE3223
6 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2906
ID:
2906
4.
Full record GDS2672

Embryonic V6.5 stem cell differentiation in vitro (MG-430B)

Analysis of V6.5 embryonic stem cells differentiating into embryoid bodies in vitro. Cells examined at various time points up to 14 days after inducing differentiation. Results provide insight into the molecular mechanisms that drive embryonic stem cell differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 11 time sets
Platform:
GPL340
Series:
GSE3231
33 Samples
Download data: CEL, EXP
5.
Full record GDS2669

Embryonic J1 stem cell differentiation in vitro (MG-430B)

Analysis of J1 embryonic stem cells differentiating into embryoid bodies in vitro. Cells examined at various time points up to 14 days after inducing differentiation. Results provide insight into the molecular mechanisms that drive embryonic stem cell differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 11 time sets
Platform:
GPL340
Series:
GSE3749
33 Samples
Download data: CEL, EXP
6.
Full record GDS2667

Embryonic R1 stem cell differentiation in vitro (MG-430B)

Analysis of R1 embryonic stem cells differentiating into embryoid bodies in vitro. Cells examined at various time points up to 14 days after inducing differentiation. Results provide insight into the molecular mechanisms that drive embryonic stem cell differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 11 time sets
Platform:
GPL340
Series:
GSE2972
33 Samples
Download data: CEL, EXP
7.
Full record GDS2483

Ras-associated binding protein 3A mutations effect on brain cortices and hippocampi (MG-430B)

Analysis of brain cortices and hippocampi of ras-associated binding protein (Rab) 3A D77G point or knockout mutants. Rab3a is a neuronal GTP-binding protein that binds synaptic vesicles and regulates synaptic transmission. The D77G point mutant exhibits anomalies in circadian behavior.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 genotype/variation, 2 other, 2 tissue sets
Platform:
GPL340
Series:
GSE6527
36 Samples
Download data: CEL
8.
Full record GDS2308

Akt1 serine-threonine protein kinase activation effect on the heart (MG-430B)

Analysis of hearts after acute or chronic induction of a transgenic Akt1 kinase. Acute activation results in reversible hypertrophy, while chronic activation induces transition to failure. Results provide insight into the mechanisms involved in the development of cardiac hypertrophy and failure.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 5 protocol sets
Platform:
GPL340
Series:
GSE3383
18 Samples
Download data
DataSet
Accession:
GDS2308
ID:
2308
9.
Full record GDS2281

Uniparental duplication of chromosome 7 regions effect on embryo and newborn brain (MG-430B)

Analysis of embryos and brains of newborns with maternal or paternal uniparental duplications (UpDps) of chromosome 7 regions. Translocation used to produce UpDps. Results provide insight into the extent and distribution of imprinted genes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 tissue sets
Platform:
GPL340
Series:
GSE4870
4 Samples
Download data: CEL, EXP
10.
Full record GDS2254

Mammary epithelial stem cells (MG-430B)

Analysis of mammary stem cells, colony-forming progenitor cells, and myoepithelial cells. Results provide insight into the molecular mechanisms regulating mammary stem cell self-renewal and differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type sets
Platform:
GPL340
Series:
GSE3711
9 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2254
ID:
2254
11.
Full record GDS2152

RNA helicase p68/p72 knockdown effect on skeletal muscle cells (MG-430B)

Analysis of C2C12 skeletal muscle cells following shRNA knockdown of the RNA helicases p68 and p72. C2C12 myoblasts cultured in differentiation medium to induce differentiation into skeletal muscle cells. Results provide insight into the role of p68/p72 in skeletal muscle cell differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 growth protocol sets
Platform:
GPL340
Series:
GSE5305
12 Samples
Download data: CEL
DataSet
Accession:
GDS2152
ID:
2152
12.
Full record GDS2060

Transcription factor Egr3 expression effect on primary myotubes (MG-430B)

Analysis of primary myotubes expressing wild-type or inactive truncated Egr3. Transcription factor Egr3 activity is critical for the development of muscle spindles, skeletal muscle stretch receptors that mediate axial and limb proprioception.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL340
Series:
GSE1998
4 Samples
Download data: CEL
DataSet
Accession:
GDS2060
ID:
2060
13.
Full record GDS2031

Hoxa11/Hoxd11 null mutation effect on embryonic kidney development (MG-430B)

Analysis of kidneys from Hoxa11/Hoxd11 double null mutants at various embryonic ages up to E16.5. Hox11 genes play critical roles in kidney development. Results provide insight into the molecular mechanisms of Hox11 function in kidney development.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 age, 2 genotype/variation sets
Platform:
GPL340
Series:
GSE3808
14 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2031
ID:
2031
14.
Full record GDS2005

Lymphotoxin-beta receptor signaling inhibition effect on lymph nodes: time course (MG-430B)

Analysis of lymph nodes from animals treated with soluble lymphotoxin-beta receptor (LTbetaR)-immunoglobulin fusion protein (LTbetaR-Ig) for up to 35 days. LTbetaR-Ig inhibits LTbetaR activation, important in the differentiation of lymphoid germinal centers and follicular dendritic cells.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 6 time sets
Platform:
GPL340
Series:
GSE2124
18 Samples
Download data: CEL
DataSet
Accession:
GDS2005
ID:
2005
15.
Full record GDS1932

Retinoblastoma-like p107 knockout effect on neurospheres (MG-430B)

Expression profiling of neurospheres cultured from the brain of embryonic day 13.5 p107 knockout embryos. p107 knockout animals exhibit enhanced stem cell self-renewal and have an increased number of stem cells.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL340
Series:
GSE3779
7 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS1932
ID:
1932
16.
Full record GDS1766

Extraocular and hindlimb skeletal muscle cell differentiation: time course (MG-430B)

Analysis of cell lines derived from extraocular (EOM) and gastrocnemius skeletal muscle allotypes at various time points up to 48 hours following induction of myogenesis. Results provide insight into the early developmental mechanisms underlying the formation of skeletal muscle classes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type, 5 time sets
Platform:
GPL340
Series:
GSE4463
30 Samples
Download data: CEL
DataSet
Accession:
GDS1766
ID:
1766
17.
Full record GDS1610

Inbred Long Sleep and Inbred Short Sleep model of ethanol sensitivity: cerebellum (MG-430B)

Comparison of cerebella of Inbred Long Sleep (ILS) and Inbred Short Sleep (ISS) animals. ILS animals are more sensitive than ISS animals to ethanol. Initial sensitivity to ethanol is a predictor of alcohol abuse. Results provide insight into the molecular basis of differential ethanol sensitivity.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 strain sets
Platform:
GPL340
Series:
GSE3071
4 Samples
Download data: CEL, EXP
18.
Full record GDS1501

Mechanical stimulation effect on fibroblasts from various fetal tissues (MG-430B)

Expression profiling of fetal fibroblasts from tendon, skin, and cornea following mechanical stimulation by fluid flow. Fibroblasts isolated from embryos at 19 days post conception. Results provide insight into differences among fibroblasts from different tissues and response to linear shear stress.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 cell line, 2 stress sets
Platform:
GPL340
Series:
GSE3486
18 Samples
Download data: CEL, EXP
19.
Full record GDS1446

Transcription factor Oct-1 deficient fibroblast response to ionizing radiation (430B)

Expression profiling of Oct-1 deficient 3T3-immortalized embryonic fibroblasts exposed to gamma radiation. Oct-1 is a POU domain transcription factor. Results provide insight into the role of Oct-1 in the adaptation to cellular stress.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets
Platform:
GPL340
Series:
GSE2084
16 Samples
Download data: CEL
DataSet
Accession:
GDS1446
ID:
1446
20.
Full record GDS1343

Forelimb and hindlimb embryonic autopod comparison (MG-430B)

Analysis of forelimb and hindlimb autopod tissues at embryonic day 12.5. Results provide insight into the molecular mechanisms regulating the formation of forelimbs and hindlimbs.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 tissue sets
Platform:
GPL340
Series:
GSE2560
6 Samples
Download data: CEL
DataSet
Accession:
GDS1343
ID:
1343
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