Related DataSets for GEO DataSets (Select 2408) - GEO DataSets

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Select item 24081.

B cell-activating factor of the TNF family effect on B cells

Analysis of total and polysomal RNAs from B cells stimulated with B cell-activating factor of the TNF family (BAFF). BAFF promotes B cell survival. Results provide insight into the signaling mechanisms underlying BAFF-mediated B cell survival.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 protocol sets

Platform:: GPL1261
Series:: GSE5985
4 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2408

ID:: 2408

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 36852.

Livers with Dicer1 deficient hepatocytes

Analysis of liver with hepatocytes lacking Dicer1. Dicer1 is an RNaseIII-type enzyme that cleaves both long double-stranded RNA molecules and hairpin miRNA precursors, and it is required for the processing of all miRNAs. Results provide insight into the function of Dicer1 in the liver.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE11899
10 Samples

Download data: CEL

DataSet

Accession:: GDS3685

ID:: 3685

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 36843.

Catecholamine stress effect on hearts of beta2 adrenergic receptor deficient mutants

Analysis of hearts of various wild type and beta2 adrenergic receptor (B2KO) deficient animals subjected to catecholamine (CA) stress by beta receptor agonist isoproterenol treatment. B2KO mutants and FVB wild type animals develop left ventricle systolic dysfunction in response to CA stress.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 4 strain sets

Platform:: GPL1261
Series:: GSE12413
86 Samples

Download data: CEL

DataSet

Accession:: GDS3684

ID:: 3684

Select item 36834.

ACE inhibitor captopril effect on atherosclerosis model: aorta

Analysis of aorta from hypercholesterolemic, apolipoprotein E (APOE)-null animals treated with captopril, an angiotensin-converting enzyme (ACE) inhibitor. Captopril attenuates atherosclerosis. Results provide insight into the molecular basis of the antiatherosclerotic effect of captopril.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 disease state, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE19286
6 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3683

ID:: 3683

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 36805.

Calreticulin deficiency effect on embryonic stem cell line

Analysis of D3 embryonic stem cells lacking calreticulin (CRT). CRT is a calcium binding protein.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE13805
7 Samples

Download data: CEL

DataSet

Accession:: GDS3680

ID:: 3680

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 36716.

Maternal hypercholesterolemia effect on offspring: carotid a

Analysis of carotid artery from 20 week old, heterozygous apolipoprotein E deficient (apoE-/+) progeny of apoE+/+ or apoE-/- mothers. Results provide insight into whether in utero exposure to maternal atherosclerotic risk factors increases susceptibility to cardiovascular disease in adult life.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE6134
7 Samples

Download data: CEL

DataSet

Accession:: GDS3671

ID:: 3671

Select item 36707.

Hypochlorous acid effect on macrophage cell line: dose response

Analysis of macrophage RAW 264.7 cells treated with up to 3.5 mM hypochlorous acid (HOCl). HOCl exposure can occur from chlorine gas inhalation or from endogenous sources of HOCl, such as respiratory burst by phagocytes. Results provide insight into the dose-dependent molecular response to HOCl.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 8 dose sets

Platform:: GPL1261
Series:: GSE15457
25 Samples

Download data: CEL

DataSet

Accession:: GDS3670

ID:: 3670

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 36678.

Transgenic model of selective ATF6 activation: heart

Analysis of heart left ventricle from ATF6-MER transgenic (TG) males, treated with tamoxifen to confer activation to ATF6-MER. Activating ATF6 protects the heart of TG animals from endoplasmic reticulum stress. Results provide insight into molecular mechanisms underlying this protective effect.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE8322
12 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3667

ID:: 3667

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 36639.

Zinc finger transcription factor Gata4 inactivation effect on endothelial-derived cells

Analysis of atrioventricular canals (AVC) from E9.5 hearts with endocardial-restricted Gata4 inactivation. The mutant endothelium failed to undergo epithelial-mesenchymal transition (EMT), resulting in hypocellular AV cushions. Results provide insight into the role of Gata4 in endocardial cell EMT.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE5298
8 Samples

Download data: CEL

DataSet

Accession:: GDS3663

ID:: 3663

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 366210.

A2B adenosine receptor deficient heart response to ischemic preconditioning and subsequent reperfusion

Analysis of heart of A2B adenosine receptor (A2BAR) deficient animals subjected to ischemic preconditioning (IP) and subsequent reperfusion. IP induces cardioprotection to prolonged ischemia. A2BAR deficient animals do not respond to IP and have increased susceptibility to acute myocardial ischemia.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation, 2 protocol sets

Platform:: GPL1261
Series:: GSE19875
12 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3662

ID:: 3662

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 366011.

Particulate matter effect on dilated cardiomyopathy model: lung and heart

Analysis of lung and heart left ventricle from CD-1 animals with congestive heart failure (CHF) exposed to ambient particulate matter (PM). Results provide insight into potential mechanistic links between PM exposure and increased cardiovascular morbidity and mortality observed in people with CHF.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 agent, 2 genotype/variation, 2 tissue sets

Platform:: GPL1261
Series:: GSE17478
24 Samples

Download data: CEL

DataSet

Accession:: GDS3660

ID:: 3660

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 365912.

Transcriptional regulator Fog2 knockout effect on adult heart

Analysis of heart ventricles of 6-week-old animals deficient for zinc finger transcriptional regulator FOG2 (friend of Gata 2, also known as ZFPM2). Fog2-null adults have severely depressed ventricular function and die at 8-14 weeks. Results provide insight into the role of Fog2 in the adult heart.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE15078
6 Samples

Download data: CEL

DataSet

Accession:: GDS3659

ID:: 3659

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 365713.

Diabetic retina

Analysis of retina from adult CD-1 animals injected with streptozotocin on three successive days. This drug selectively destroys the beta-islet cells of the pancreas thereby inducing diabetes. Results provide insight into the molecular mechanisms underlying neural degeneration of the retina.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 disease state, 3 time sets

Platform:: GPL1261
Series:: GSE12610
5 Samples

Download data: CEL

DataSet

Accession:: GDS3657

ID:: 3657

GEO Profiles Analyze DataSet

Select item 365414.

Sphingosine 1-phosphate lyase deficiency effect on liver

Analysis of liver of animals lacking sphingosine 1-phosphate lyase (S1P). In addition to the expected increase of sphingoid base phosphates, other sphingolipids are elevated in the sera and livers of S1P deficient animals. Results provide insight into the role of S1P in lipid metabolic pathways.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE18745
6 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3654

ID:: 3654

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 364715.

Wolfram syndrome model: temporal lobe

Analysis of temporal lobes of C57B6 and 129S6 animals deficient for the Wfs1 protein. WFS1 gene mutations cause the Wolfram syndrome, an autosomal recessive disorder characterized by diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. WFS1 is expressed in the temporal lobe.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 genotype/variation, 2 strain sets

Platform:: GPL1261
Series:: GSE15293
37 Samples

Download data: CEL

DataSet

Accession:: GDS3647

ID:: 3647

Select item 364116.

Methyltransferase Hypb deficiency effect on the yolk sac during development

Analysis of yolk sacs from E9 and E10.5 embryos lacking Hypb, a histone H3 lysine 36-specific methytransferase. Hypb deficiency results in lethality at E10.5-E11.5 and severe vascular defects in the embryo, yolk sac, and placenta. Results provide insight into the function of Hypb in development.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 development stage, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE10113
12 Samples

Download data: CEL

DataSet

Accession:: GDS3641

ID:: 3641

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 363717.

Myostatin depletion effect on mature skeletal muscle

Analysis of mature skeletal muscle depleted for the TBFb protein myostatin (MSTN). MSTN inhibits muscle differentiation and growth. MSTN deficiency during development results in muscle hypertrophy. Results provide insight into the effect of reducing MSTN activity after normal muscle development.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL1261
Series:: GSE15349
10 Samples

Download data: CEL

DataSet

Accession:: GDS3637

ID:: 3637

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 363618.

Matricellular glycoprotein SPARC deficiency effect on lens epithelium

Analysis of lens epithelia from animals lacking SPARC. SPARC is a matricellular glycoprotein involved in regulation of extracellular matrix, growth factors, adhesion, and migration. Results provide insight into the function of SPARC in the lens.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE13402
7 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3636

ID:: 3636

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 362919.

Rod-derived cone viability factor deficiency effect on the retina

Analysis of retinas from animals lacking the rod-derived cone viability factor (RdCVF). RdCVF is encoded by the Nxnl1 gene. Cone loss in animal models of retinitis pigmentosa is reduced by RdCVF protein therapy. Results provide insight into the physiological role of RdCVF in the retina.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 3 genotype/variation sets

Platform:: GPL1261
Series:: GSE13869
8 Samples

Download data: CEL

DataSet

Accession:: GDS3629

ID:: 3629

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 362220.

Nrf2-deficient lung response to cigarette smoke: dose response and time course

Analysis of lungs from transcription factor Nrf2-deficient animals exposed to cigarette smoke (CS) at various doses and for various lengths of time with or without a subsequent recovery period. Results provide insight into the impact of Nrf2 in acute and subchronic smoking scenarios.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 agent, 4 dose, 2 genotype/variation, 3 protocol, 3 time sets

Platform:: GPL1261
Series:: GSE18344
110 Samples

Download data: CEL

DataSet

Accession:: GDS3622

ID:: 3622

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