GEO DataSet Links for BioProject (Select 97577) - GEO DataSets

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Items: 2

Select item 2000061341.

Offsprings of crosses between hypercholesterolemic and normocholesterolemic parents LUMC-HKG-ApoE-Atherosclerosis

(Submitter supplied) Enhanced prenatal fatty streak formation in human fetuses has been associated with maternal hypercholesterolemia. However, the possible roles of maternal genetic background and in utero environment on development of atherosclerosis in adult life have not been unraveled. We generated genetically identical heterozygous apoE-deficient mice offspring with a different maternal background to study the intrauterine effect of maternal genotype and associated hypercholesterolemia on the developing vascular system. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3671
Platform:: GPL1261
7 Samples

Download data: CEL

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Accession:: GSE6134

ID:: 200006134

Select item 36712.

Maternal hypercholesterolemia effect on offspring: carotid a

Analysis of carotid artery from 20 week old, heterozygous apolipoprotein E deficient (apoE-/+) progeny of apoE+/+ or apoE-/- mothers. Results provide insight into whether in utero exposure to maternal atherosclerotic risk factors increases susceptibility to cardiovascular disease in adult life.