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Single nuclei transcriptomics of human and monkey striatum implicates DNA damage, neuroinflammation, and neurodegeneration signaling in opioid use disorder

(Submitter supplied) The striatum in the brain is involved in various behavioral functions, including reward, and disease processes, such as opioid use disorder (OUD). Further understanding of the role of striatal subregions in reward behaviors and their potential associations with OUD requires molecular identification of specific striatal cell types in human brain. The human striatum contains subregions based on different anatomical, functional, and physiological properties, with the dorsal striatum further divided into caudate and putamen. more...
Organism:
Macaca mulatta; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL18573 GPL27943
40 Samples
Download data
Series
Accession:
GSE233279
ID:
200233279

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