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Items: 3

1.

Dynamics of global gene expression changes during mouse preimplantation development

(Submitter supplied) Understanding preimplantation development is important both for basic reproductive biology and for practical applications including regenerative medicine and livestock breeding. Global expression profiles revealed and characterized the distinctive patterns of maternal RNA degradation and zygotic gene activation, including two major transient waves of de novo transcription. The first wave corresponds to zygotic genome activation (ZGA); the second wave, named mid-preimplantation gene activation (MGA), precedes the dynamic morphological and functional changes from the morula to blastocyst stage. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Datasets:
GDS578 GDS579
Platform:
GPL870
64 Samples
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Series
Accession:
GSE936
ID:
200000936
2.
Full record GDS579

Zygotic gene activation

Characterization of zygotic gene activation (ZGA) and influence of maternal transcripts. Embryos cultured until 2-cell stage with inhibitors of transcription (α-amanitine), DNA replication (aphidicolin) and protein synthesis (cycloheximide).
Organism:
Mus musculus
Type:
Expression profiling by array, log ratio, 5 agent, 4 development stage sets
Platform:
GPL870
Series:
GSE936
36 Samples
Download data
DataSet
Accession:
GDS579
ID:
579
3.
Full record GDS578

Preimplantation development

Dynamics of global gene expression changes during preimplantation development. Unfertilized eggs, fertilized egg, 2-cell embryos, 4-cell embryos, 8-cell embryos, morulae and blastocysts examined.
Organism:
Mus musculus
Type:
Expression profiling by array, log ratio, 7 development stage sets
Platform:
GPL870
Series:
GSE936
28 Samples
Download data
DataSet
Accession:
GDS578
ID:
578
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