Distinct immunological and molecular signatures predict influenza vaccine responsiveness in the elderly - - GEO DataSets

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Distinct immunological and molecular signatures predict influenza vaccine responsiveness in the elderly

(Submitter supplied) The significant economic burden and high mortality rates resulting from seasonal influenza outbreaks, especially in high risk groups such as the elderly, represent an important public health problem. The prevailing inadequate efficacy of seasonal vaccines, both conventional and elderly-tailored, is a crucial bottleneck. Consequentially, understanding immunological and molecular mechanisms resulting in differential influenza vaccine responsiveness is a prerequisite for the development of new or improved vaccination strategies. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
100 Samples

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Accession:: GSE211368

ID:: 200211368

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