GEO DataSets

(Submitter supplied) Purpose: To identify the genome binding sites of Cren7 and Sso7D, and to determine whether binding patterns differ between wild type and an epigenetically evolved strain in which they are heritably hypomethylated. Because methylated residues were solvent facing, it was predicted that binding patterns would not change between the strains. Methods: Chromosomal fragments 300-500bp long were immunoprecipitated in triplicate using polyclonal antibody serum for Cren7 or Sso7D and sequenced using Illumina Hiseq. more...

Organism:

Saccharolobus solfataricus

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL27594

24 Samples

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