The activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-kappaB p65 II - - GEO DataSets - NCBI

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The activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-kappaB p65 II

(Submitter supplied) The inflammatory gene response requires activation of the protein kinase TAK1, but it is currently unknown how TAK1-derived signals coordinate transcriptional programs in the genome. We determined the genome-wide binding of the TAK1-controlled NF-κB subunit p65 in relation to active enhancers and promoters of transcribed genes by ChIP-seq experiments. Out of 35,000 active enhancer regions, 410 H3K4me1-positive enhancers show interleukin (IL)-1-induced H3K27ac and p65 binding. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
10 Samples

Download data: TXT

Series

Accession:: GSE64237

ID:: 200064237

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GEO DataSet Links for BioProject (Select 270505) (1)
GEO DataSets
The activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-...
The activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-kappaB p65 II
Accession: GSE64237

GEO DataSets
PMC Links for Gene (Select 127830721) (1)
PMC
ATPase subunit 1 (mitochondrion) [Meniocus linifolius]
ATPase subunit 1 (mitochondrion) [Meniocus linifolius]
gi|2666697025|ref|YP_011021740.1|

Protein
G protein-coupled receptor 87 [Homo sapiens]
G protein-coupled receptor 87 [Homo sapiens]
gi|108742076|gb|AAI17566.1|

Protein

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