GEO DataSet Links for BioProject (Select 246153) - GEO DataSets

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Items: 2

Select item 2000572751.

Genome-wide analysis of gene expression in lung cells from metformin treated Mycobacterium tuberculosis infected mice

(Submitter supplied) Analysis of Metfromin induced changes in the lung cells of Mycobacterium tuberculosis infected mouse at gene expression level. The hypothesis tested in the present study was whether metformin has any effect on the host immune response in Mycobacterium tuberculosis infected mice? Results provide important information on the effect of metformin on the inflammatory response and immune activation associated with mycobacterial infection. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS5436
Platform:: GPL6887
14 Samples

Download data: TXT

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Accession:: GSE57275

ID:: 200057275

Select item 54362.

Metformin effect on Mycobacterium tuberculosis-infected lung

Analysis of lung from M. tuberculosis (MT)-infected C57BL/6 mice treated with metformin (MET). The antidiabetic drug MET is an activating agent of adenosine monophosphate-activated protein kinase (AMPK). Results provide insight into the potential use of MET as adjunct antituberculosis therapy.