(Submitter supplied) Ferric uptake regulator (Fur) is the major regulator of iron acquisition in Escherichia coli and other bacteria. In the present study, the role of Fur in anaerobic S. enterica serovar Typhimurium was determined by transcriptome analysis, reporter assays, and enzymatic assays. In anaerobic Δfur, 298 genes were differentially expressed. In general, Fur repressed genes required for iron acquisition/storage, metabolism, electron transport, oxidative/nitrosative stress, and modulators of virulence.
more...- Organism:
- Salmonella enterica subsp. enterica serovar Typhimurium; Salmonella
- Type:
- Expression profiling by array
- Platform:
- GPL1835
- 6 Samples
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