Integrated electrophysiological and genomic profiles of single cells reveal spiking tumor cells in human glioma [scRNA-seq] - - GEO DataSets

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Integrated electrophysiological and genomic profiles of single cells reveal spiking tumor cells in human glioma [scRNA-seq]

(Submitter supplied) Prior studies have described the complex interplay that exists between glioma cells and neurons, however, the electrophysiological properties endogenous to tumor cells remain obscure. To address this, we employed Patch-sequencing on human glioma specimens and found that one third of patched cells in IDH mutant (IDHmut) tumors demonstrate properties of both neurons and glia by firing single, short action potentials. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18573
6 Samples

Download data: MTX, TSV

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Accession:: GSE271959

ID:: 200271959

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