FLI1 promotes IFN-γ-induced kynurenine production to impair anti-tumor immunity (RNA-Seq) - - GEO DataSets

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FLI1 promotes IFN-γ-induced kynurenine production to impair anti-tumor immunity (RNA-Seq)

(Submitter supplied) Nasopharyngeal carcinoma (NPC)-mediated immunosuppression within the tumor microenvironment (TME) frequently culminates in the failure of otherwise promising immunotherapies, underscoring the imperative to develop strategies to counteract the tumor's ability to foster an immunologically "cold" TME. In this study, we identify tumor-intrinsic FLI1 as a critical mediator in impairing T cell anti-tumor immunity through bioinformatic analysis. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
3 Samples

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Accession:: GSE247897

ID:: 200247897

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