iPSC-derived microglia export cholesterol to neuronal cells in human brain organoids and promote their maturation - - GEO DataSets

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iPSC-derived microglia export cholesterol to neuronal cells in human brain organoids and promote their maturation

(Submitter supplied) Microglia are specialised brain-resident macrophages that arise from primitive macrophages colonising the embryonic brain. Microglia contribute to multiple aspects of brain development, but their precise roles in early human brain remain poorly understood due to limited access to relevant tissues. The generation of brain organoids from induced human pluripotent stem cells (iPSC) recapitulates some key features of human embryonic brain development, but current approaches do not incorporate microglia and thus are lacking. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
6 Samples

Download data: TXT

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Accession:: GSE241127

ID:: 200241127

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