GEO DataSets

(Submitter supplied) Growth rate can be genetically modified in many vertebrates by domestication and selection, and more recently by transgenesis overexpressing growth factor genes (e.g. growth hormone, GH). While the phenotypic end consequence is similar, it is currently not clear whether the same modifications to physiological pathways are occurring in both genetic processes, nor to what extent they may interact when combined. more...

Organism:

Oncorhynchus mykiss; Oncorhynchus tshawytscha; Salmo salar; Coregonus clupeaformis; Osmerus mordax

Type:

Expression profiling by array

Platform:

GPL2716

30 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Oncorhynchus tshawytscha; Danio rerio; Coregonus clupeaformis; Osmerus mordax; Oncorhynchus mykiss; Salmo salar

Type:

Expression profiling by array

Platforms:

GPL14375 GPL2716

28 Samples

Download data: PAIR, TXT

(Submitter supplied) Juvenile rainbow trout were fed Biodiet starter (4% body weight per day) with MeHg added at 0, 0.5, 5 and 50 ppm for six weeks. Atomic absorption spectrometry was applied to measure the level of MeHg in the whole fish body. Trout at six weeks were sampled from each group for gene expression analysis by cGRASP 16K cDNA microarrays. MeHg-exposed rainbow trout did not show overt signs of toxicity, nor were significant differences seen in mortality, length, mass, or condition factor. more...

Organism:

Oncorhynchus mykiss; Oncorhynchus tshawytscha; Salmo salar; Coregonus clupeaformis; Osmerus mordax

Type:

Expression profiling by array

Platform:

GPL2716

4 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Osmerus mordax; Oncorhynchus mykiss; Oncorhynchus tshawytscha; Salmo salar; Coregonus clupeaformis

Type:

Expression profiling by array

Platforms:

GPL16961 GPL10770

31 Samples

Download data: TXT

(Submitter supplied) We investigated the effects of chronic TCDD exposure on global gene expression in developing rainbow trout (Oncorhynchus mykiss). Juvenile rainbow trout(0.18±0.01g) were fed Biodiet starter with TCDD added at 0, 0.1, 1, 10 and 100ppb, and ten fish were sampled and pooled from 10 ppb group at 7, 14, 28 and 42 days for microarray experiments after initiation of the exposure. Gene expression analysis was performed using the Genomics Research on All Salmonids Project (cGRASP) 16K cDNA microarrays. more...

Organism:

Osmerus mordax; Oncorhynchus mykiss; Salmo salar; Oncorhynchus tshawytscha; Coregonus clupeaformis

Type:

Expression profiling by array

Platform:

GPL10770

16 Samples

Download data: TXT

(Submitter supplied) We investigated the effects of chronic TCDD exposure on global gene expression in developing rainbow trout (Oncorhynchus mykiss). Juvenile rainbow trout (0.18±0.01g) were fed Biodiet starter with TCDD added at 0, 0.1, 1, 10 and 100ppb, and ten fish were sampled and pooled from each group for microarray experiments at 28 days after initiation of the exposure. Gene expression analysis was performed using the Genomics Research on All Salmonids Project (cGRASP) 16K cDNA microarrays. more...

Organism:

Osmerus mordax; Oncorhynchus mykiss; Salmo salar; Oncorhynchus tshawytscha; Coregonus clupeaformis

Type:

Expression profiling by array

Platform:

GPL16961

15 Samples

Download data: TXT

(Submitter supplied) Parental effects represent an important source of variation in offspring phenotypes. Depending on the specific mechanisms involved, parental effects may be caused to different degrees by either the maternal or paternal parent, and these effects may in turn act at different stages of development. In order to detect parental effects acting on gene transcription regulation and length phenotype during ontogeny, the transcriptomic profiles of two reciprocal hybrids from Laval × Rupert and Laval × domestic populations of brook charr were compared at hatching, yolk sac resorption, and 15 weeks after exogenous feeding. more...

Organism:

Oncorhynchus mykiss; Salmo salar; Oncorhynchus tshawytscha; Osmerus mordax; Salvelinus fontinalis; Coregonus clupeaformis

Type:

Expression profiling by array

Platform:

GPL2716

96 Samples

Download data: TXT

(Submitter supplied) To identify genes involved in the developmental process of Atlantic salmon smoltification, gene expression was compared between smolt and parr in tissues involved in osmoregulation (gill), metabolism (liver), imprinting (olfactory rosettes) and neuroendocrine control (hypothalamus and pituitary). Tissue samples were harvested from laboratory-reared parr and smolts on the same date. Smolts were distinguished from parr by size and appearance; developmental status was confirmed by physiological assays.

Organism:

Oncorhynchus mykiss; Salmo salar; Oncorhynchus tshawytscha; Osmerus mordax; Coregonus clupeaformis

Type:

Expression profiling by array

Platform:

GPL2716

38 Samples

Download data: TXT

(Submitter supplied) Exposure to environmental contaminants like nonylphenol can disrupt smolt development and may be a contributing factor in salmon population declines. We used GRASP 16K cDNA microarrays to identify genes that are differentially expressed in the liver, gill, hypothalamus, pituitary, and olfactory rosettes of Atlantic salmon smolts treated with nonylphenol compared to control smolts. Nonylphenol treatment was confirmed using physiological assays: nonylphenol-treatment significantly decreased gill Na+,K+-ATPase activity and plasma cortisol and T3 levels.

Organism:

Osmerus mordax; Oncorhynchus mykiss; Oncorhynchus tshawytscha; Salmo salar; Coregonus clupeaformis

Type:

Expression profiling by array

Platform:

GPL2716

40 Samples

Download data: TXT

(Submitter supplied) We collected sockeye salmon from the Fraser River, British Columbia, and held them at ecologically relevant temperatures (14C and 19C) determine the effect of elevated water temperature on cellular processes in non-lethally sampled gill tissue and blood plasma over a period of seven days that represents a significant portion of their upstream migration. Time-matched fish that died prematurely over the course of the holding study were also sampled for gill tissue and the transcriptomic responses in moribund fish were compared with surviving fish. more...

Organism:

Osmerus mordax; Coregonus clupeaformis; Oncorhynchus mykiss; Oncorhynchus nerka; Salmo salar; Oncorhynchus tshawytscha

Type:

Expression profiling by array

Platform:

GPL2716

40 Samples

Download data: TXT

(Submitter supplied) Considerable interest and controversy has arisen over the potential effects of seismic surveys carried out during exploration for oil and gas deposits. Regarding fish, there is a concern that intense sound sources, such as seismic airguns, may injure their auditory system. In this study, salmonid cDNA microarrays and quantitative reverse transcription – polymerase chain reaction (QPCR) were used to identify and study a responsive gene set in the inner ear of Atlantic salmon (Salmo salar) following seismic airgun exposure. more...

Organism:

Salmo salar; Coregonus clupeaformis; Oncorhynchus mykiss; Oncorhynchus tshawytscha; Osmerus mordax

Type:

Expression profiling by array

Platform:

GPL10770

4 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Coregonus clupeaformis; Oncorhynchus mykiss; Oncorhynchus nerka; Salmo salar; Oncorhynchus tshawytscha; Osmerus mordax

Type:

Expression profiling by array

Platforms:

GPL8904 GPL2716

128 Samples

Download data: TXT

(Submitter supplied) The long-term viability of Pacific salmon stocks and the fisheries they support are threatened if large numbers die prematurely en-route to spawning grounds. Physiological profiles that were correlated with the fate of wild sockeye salmon during river migration were discovered using functional genomics studies on biopsied tissues. Three independent biotelemetry studies tracked the biopsied fish after tagging in the marine environment over 200 km from the Fraser River, in the lower river 69 km from the river mouth and at the spawning grounds. more...

Organism:

Salmo salar; Coregonus clupeaformis; Oncorhynchus mykiss; Oncorhynchus tshawytscha; Oncorhynchus nerka; Osmerus mordax

Type:

Expression profiling by array

Platform:

GPL2716

104 Samples

Download data: TXT

(Submitter supplied) The long-term viability of Pacific salmon stocks and the fisheries they support are threatened if large numbers die prematurely en-route to spawning grounds. Physiological profiles that were correlated with the fate of wild sockeye salmon during river migration were discovered using functional genomics studies on biopsied tissues. Three independent biotelemetry studies tracked the biopsied fish after tagging in the marine environment over 200 km from the Fraser River, in the lower river 69 km from the river mouth and at the spawning grounds. more...

Organism:

Osmerus mordax; Coregonus clupeaformis; Oncorhynchus mykiss; Oncorhynchus nerka; Salmo salar; Oncorhynchus tshawytscha

Type:

Expression profiling by array

Platform:

GPL2716

35 Samples

Download data: TXT

(Submitter supplied) The retention of a nucleus in the mature state of fish red blood cells (RBCs), and the ability to easily collect and manipulate blood in non-terminal experiments, makes it an ideal tissue on which to study the cellular stress response in fish. Through the use of the cGRASP 16K salmonid microarray, we are currently investigating differences in RBC global gene transcription in fish held under control conditions (12C) and exposed to heat stress (one hour at 25C followed by recovery at 12C). more...

Organism:

Coregonus clupeaformis; Oncorhynchus tshawytscha; Oncorhynchus mykiss; Salmo salar; Osmerus mordax

Type:

Expression profiling by array

Platform:

GPL2716

32 Samples

Download data: TXT

(Submitter supplied) The rainbow smelt (Osmerus mordax, Mitchill, 1814) is an anadromous teleost that overwinters in the estuaries and inshore waters along the North American Atlantic coastline. In the winter months, smelt avoid freezing in subzero temperatures by the production of antifreeze proteins and high levels of glycerol. Glycerol production (glyceroneogenesis) occurs in the liver via a branch point in glycolysis and gluconeogenesis and is directly activated by low temperature. more...

Organism:

Coregonus clupeaformis; Oncorhynchus mykiss; Salmo salar; Oncorhynchus tshawytscha; Osmerus mordax

Type:

Expression profiling by array

Platform:

GPL10770

12 Samples

Download data: TXT

(Submitter supplied) Genetic analyses of speciation have focused nearly exclusively on retrospective analyses of reproductive isolation between highly divergent species. Yet, a full understanding of the speciation process must encompass analysis of the consequences of genomic divergence in young lineages still capable of exchanging genes under natural conditions. The accumulation of conditionally neutral genetic variation may lead to the evolution of divergent gene networks. more...

Organism:

Salmo salar; Coregonus clupeaformis; Oncorhynchus mykiss; Oncorhynchus tshawytscha; Osmerus mordax

Type:

Expression profiling by array

Platform:

GPL2716

64 Samples

Download data: TXT

(Submitter supplied) The genetic mechanisms underlying hybridization are poorly understood despite their potentially important roles in speciation processes, adaptative evolution, and agronomical innovation. In this study, transcription profiles were compared among three populations of brook charr and their hybrids using microarrays to assess the influence of hybrid origin on modes of transcription regulation inheritance and on the mechanisms underlying growth. more...

Organism:

Osmerus mordax; Oncorhynchus mykiss; Oncorhynchus tshawytscha; Salmo salar; Salvelinus fontinalis; Coregonus clupeaformis

Type:

Expression profiling by array

Platform:

GPL2716

96 Samples

Download data: TXT

(Submitter supplied) Despite the progress achieved in elucidating the ecological mechanisms of adaptive radiation, there has been little focus on documenting the extent of adaptive differentiation in physiological functions during this process. Moreover, a thorough understanding of the genomic basis underlying phenotypic adaptive divergence is still in its infancy. One important evolutionary process for which causal genetic mechanisms are largely unknown pertains to life-history trade-offs. more...

Organism:

Salmo salar; Osmerus mordax; Oncorhynchus mykiss; Coregonus clupeaformis; Oncorhynchus tshawytscha

Type:

Expression profiling by array

Platform:

GPL2716

48 Samples

Download data: TXT

(Submitter supplied) Rainbow smelt (Osmerus mordax) are freeze-resistant fish that accumulate glycerol and produce an antifreeze protein during winter. Quantitative reverse transcription-PCR (qPCR) and subtractive hybridization studies have revealed a few genes in smelt liver to be differentially regulated in winter in comparison with the fall when water temperatures are warmer. In order to further define the suite of processes that are regulated seasonally, we undertook a large-scale analysis of gene expression by hybridization of smelt cDNA to the salmonid 16K cGRASP cDNA microarray. more...

Organism:

Osmerus mordax; Salmo salar

Type:

Expression profiling by array

Platform:

GPL6260

3 Samples

Download data: TXT, XLS