GEO DataSets

(Submitter supplied) Defining the subcellular distribution of all human proteins and its remodeling across cellular states remains a central goal in cell biology. Here, we present a high-resolution strategy to map subcellular organization using organelle immuno-capture coupled to mass spectrometry. We apply this workflow to a cell-wide collection of membranous and membrane-less compartments. A graph-based analysis reveals the subcellular localization of over 7,600 proteins, defines spatial networks, and uncovers interconnections between cellular compartments. more...

Organism:

Human coronavirus OC43; Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL34943

2 Samples

Download data: CSV, FASTA, GTF, MTX, TSV

(Submitter supplied) Effective methods for predicting COVID-19 disease trajectories are urgently needed. Here, enzyme-linked immunosorbent assay (ELISA) and coronavirus antigen microarray (COVAM) analysis mapped antibody epitopes in the plasma of COVID-19 patients (n = 86) experiencing a wide range of disease states. The experiments identified antibodies to a 21-residue epitope from nucleocapsid (termed Ep9) associated with severe disease, including admission to the intensive care unit (ICU), requirement for ventilators, or death. more...

Organism:

Human coronavirus 229E; Human respirovirus 3; Influenza A virus; Human coronavirus NL63; Severe acute respiratory syndrome-related coronavirus; Human coronavirus OC43; Human coronavirus HKU1; Severe acute respiratory syndrome coronavirus 2; Human parainfluenza virus 4b; Influenza B virus; Human respirovirus 1; human metapneumovirus; Human respiratory syncytial virus B; Human adenovirus sp.; Homo sapiens; Human respiratory syncytial virus A; Dromedary camel coronavirus; Human orthorubulavirus 2

Type:

Protein profiling by protein array

Platform:

GPL30021

90 Samples

Download data: TXT

(Submitter supplied) 60 antigens across respiratory virus subtypes, including 11 antigens from SARS-CoV-2 expressed in either baculovirus or HEK-293 cells. All antigens were supplied by Sino Biological Inc. Purified proteins were printed onto ONCYTE AVID nitrocellulose-coated slides (Grace Bio-Labs, Bend, OR) using an OmniGrid 100 microarray printer (GeneMachines). Protocol: See manufacturer website.

Organism:

Human coronavirus 229E; Human respirovirus 3; Human parainfluenza virus 4b; Influenza A virus; Influenza B virus; Human respirovirus 1; Human coronavirus OC43; human metapneumovirus; Human respiratory syncytial virus A; Human respiratory syncytial virus B; Human coronavirus NL63; Human coronavirus HKU1; Severe acute respiratory syndrome-related coronavirus; Human adenovirus sp.; Dromedary camel coronavirus; Human orthorubulavirus 2; Severe acute respiratory syndrome coronavirus 2

1 Series

90 Samples

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