GEO DataSets

(Submitter supplied) Altered regulatory interactions during development likely underlie a large fraction of phenotypic diversity within and between species, yet identifying specific evolutionary changes remains challenging. Analysis of single-cell developmental transcriptomes from multiple species provides a powerful framework for unbiased identification of evolutionary changes in developmental mechanisms. Here, we leverage a “natural experiment” in developmental evolution in sea urchins, where a major life history switch recently evolved in the lineage leading to Heliocidaris erythrogramma, precipitating extensive changes in early development. more...

Organism:

Heliocidaris erythrogramma

Type:

Expression profiling by high throughput sequencing

Platform:

GPL34915

7 Samples

Download data: MTX, TSV

(Submitter supplied) Sea urchins are a unique system for studying developmental transistions because of the stark differences between their bilateral larval and pentaradial adult body plans. Here, we use single cell RNA-sequencing to analyze the development of Heliocidaris erythrogramma (He), a sea urchin species with an accelerated, non-feeding mode of larval development. The sequencing time course extends from early embryogenesis to roughly a day before the onset of metamorphosis in He larvae, which is a period that has not been covered by previous datasets. more...

Organism:

Heliocidaris erythrogramma

Type:

Expression profiling by high throughput sequencing

Platform:

GPL34915

5 Samples

Download data: MTX, TSV