GEO DataSets

(Submitter supplied) Tuberculosis, caused by Mycobacterium tuberculosis has remained a leading cause of death worldwide even after decades of it being declared as global health emergency by the WHO. Newer drugs with novel modes of action are urgently needed to combat the threats imposed by the constantly emerging drug resistant strains. Natural products (NPs) derived anti-mycobacterials appear lucrative because of their complex structural features and unique cellular targets they bind to. more...

Organism:

Talaromyces sp. F31

Type:

Expression profiling by high throughput sequencing

Platform:

GPL34664

4 Samples

Download data: TXT

(Submitter supplied) Identification of global target genes that their expression levels are dependent on the AcuK and the AcuM transcription factors from T. marneffei. Results provided information that the AcuK and AcuM are global regulators important for adaptation and defense against harsh environmental conditions, such as the response to iron limitation, utilization of alternative carbon sources, and antioxidation.

Organism:

Talaromyces marneffei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL33968

3 Samples

Download data: XLSX

(Submitter supplied) Talaromyces marneffei is the third most common infectious pathogen in AIDS patients and leads to the highest death rate in Guangxi, China. The lack of reliable biomarkers is one of the major obstacles in current clinical diagnosis, which largely contributes to this high mortality. Here, we present a study that aimed at identifying diagnostic biomarker candidates through genome-wide prediction and functional annotation of Talaromyces marneffei secreted proteins. more...

Organism:

Talaromyces marneffei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL33968

3 Samples

Download data: TXT

(Submitter supplied) Although many studies have focused on dimorphic switching, noncoding RNAs in Talaromyces marneffei have been neglected until now. rRNA depletion RNA-seq with or without RNase R treatment were performed in mycelium and yeast conditions of Talaromyces marneffei by to unveil the functions of circRNAs in dimorphic switching.

Organism:

Talaromyces marneffei

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL33388 GPL33387

22 Samples

Download data: CSV, GTF

(Submitter supplied) Transcriptomic profiling and real-time quantitative reverse transcription-PCR analyses revealed that TP05746 dynamically regulated the expression of genes encoding major PBDEs. Furthermore, in vitro binding experiments confirmed that TP05746 directly bound to the promoter regions of these major enzyme genes. Transcription factors mediated the regulation of plant-biomass-degrading enzyme (PBDE) gene expression in Talaromyces pinophilus.

Organism:

Talaromyces pinophilus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26713

6 Samples

Download data: FASTA, XLS

(Submitter supplied) Thermomyces lanuginosus is a thermophilic fungus whose genome encodes many carbohydrate-active enzymes involved in Avicel degradation. This study examined and compared the transcriptomes of T. lanuginosus during cultivation on Avicesl or glucose. We identified approximately 4485 genes that showed expression differences when T. lanuginosus was cultured on Avicel compared to glucose. Functional annotation of up-regulated genes showed enrichment for proteins predicted to be involved in Avicel degradation, but also many genes encoding proteins of unknown function. more...

Organism:

Thermomyces lanuginosus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20314

4 Samples

Download data: FASTA, TXT

(Submitter supplied) Penicillium marneffei (Talaromyces marneffei) is an opportunistic human pathogen that can grow in a multicellular hyphal form at 25°C or a unicellular fission yeast form at 37°C, and can switch between these two forms in response to temperature. The yeast form is found in infected individuals and represents the pathogenic phase. In response to specific environmental cues, the hyphal form can undergo asexual development (conidiation) the produce a differentiated multicellular structure called a conidiophore which produces dormant spores (conidia). more...

Organism:

Talaromyces marneffei

Type:

Expression profiling by array

Platform:

GPL17757

2 Samples

Download data: GPR

(Submitter supplied) Penicillium marneffei (Talaromyces marneffei) is an opportunistic human pathogen that can grow in a multicellular hyphal form at 25°C or a unicellular fission yeast form at 37°C, and can switch between these two forms in response to temperature. The yeast form is found in infected individuals and represents the pathogenic phase. In response to specific environmental cues, the hyphal form can undergo asexual development (conidiation) the produce a differentiated multicellular structure called a conidiophore which produces dormant spores (conidia). more...

Organism:

Talaromyces marneffei

Type:

Expression profiling by array

Platform:

GPL17756

3 Samples

Download data: GPR

(Submitter supplied) Comparative analysis of transcriptome of Penicillium marneffei PM1 grown at 25°C and 37°C

Organism:

Talaromyces marneffei PM1

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17453

4 Samples

Download data

(Submitter supplied) Mycotoxins are secondary metabolites which are produced by numerous fungi and pose a continuous challenge to the safety and quality of food commodities in South Africa. These toxins have toxicologically relevant effects on humans and animals that eat contaminated foods. In this study, a diagnostic DNA microarray was developed for the identification of the most common food-borne fungi, as well as the genes leading to toxin production. more...

Organism:

Aspergillus; Aspergillus clavatus; Fusarium oxysporum; Fusarium acuminatum; Talaromyces islandicus; Aspergillus versicolor; Penicillium fellutanum; Fusarium globosum; Pseudopithomyces chartarum; Aspergillus amstelodami; Aspergillus parasiticus; Fusarium sambucinum; Curvularia lunata; Fusarium; Talaromyces funiculosus; Bipolaris sorokiniana; Fusarium decemcellulare; Drechslera sp.; Aspergillus chevalieri; Claviceps purpurea; Alternaria alternata; Aspergillus multicolor; Fusarium subglutinans; Fusarium cerealis; Penicillium viridicatum; Penicillium corylophilum; Fusarium verticillioides; Talaromyces rugulosus; Fusarium solani; Stenocarpella maydis; Fusarium incarnatum; Aspergillus niger; Penicillium; Fusarium sporotrichioides; Fusarium graminearum; Penicillium expansum; Fusarium sp.; Fusarium avenaceum; Penicillium italicum; Aspergillus carbonarius; Fusarium anthophilum; Fusarium equiseti

Type:

Expression profiling by array; Other

Platform:

GPL9730

120 Samples

Download data: GPR, TXT

(Submitter supplied) 1. Two small insert (400-600 bp) DNA libraries of partially digested P. marneffei genomic DNA were generated using Sau3AI or TaqI cloned into the BamHI or ClaI sites of pALX223, respectively. 2. Independent colonies from both libraries were selected for the construction of the microarrays 3. Colonies (5376) were picked using the BioRobotics BioPick machine and individually placed into 384 well plates containing LB broth. more...

Organism:

Talaromyces marneffei

1 Series

2 Samples

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(Submitter supplied) 1. Two small insert (400-600 bp) DNA libraries of partially digested P. marneffei genomic DNA were generated using Sau3AI or TaqI cloned into the BamHI or ClaI sites of pALX223, respectively. 2. Independent colonies from both libraries were selected for the construction of the microarrays 3. Colonies (5376) were picked using the BioRobotics BioPick machine and individually placed into 384 well plates containing LB broth. more...

Organism:

Talaromyces marneffei

1 Series

3 Samples

Download data

(Submitter supplied) Forty food-borne fungi Protocol: 1. Oligonucleotide probes ranging in size from 16 - 23 bases were transferred to Genetix X7022 384-well plates for arraying. 2. Each well contained a final concentration of 20 µM oligonucleotide probe in 50% DMSO spotting solution (v/v). 3. Between printing runs the plates were stored at -20°C. 4. Prior to printing the plates were incubated at room temperature for 30 min to aid temperature equilibration. more...

Organism:

Aspergillus; Aspergillus amstelodami; Aspergillus clavatus; Aspergillus niger; Penicillium; Fusarium; Fusarium oxysporum; Fusarium sporotrichioides; Fusarium acuminatum; Fusarium graminearum; Alternaria alternata; Penicillium expansum; Talaromyces islandicus; Fusarium avenaceum; Aspergillus carbonarius; Fusarium subglutinans; Aspergillus versicolor; Fusarium cerealis; Fusarium equiseti; Penicillium fellutanum; Penicillium corylophilum; Fusarium verticillioides

1 Series

120 Samples

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