U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 1358

1.

Metabolic and transcriptional response to the induction of a heterologous poly-3-hydroxybutyrate pathway in Phaeodactylum tricornutum

(Submitter supplied) The marine diatom Phaeodactylum tricornutum is an emerging host for metabolic engineering, but little is known about how introduced pathways are integrated into the existing metabolic framework of the host and how this influences trans- and native-gene expression. In this study we used episomal vectors to express the heterologous poly-3-hydroxybutyrate (PHB) pathway in diatoms, which produces precursors for polymeric bioplastics from acetyl coenzyme-A (AcCoA). more...
Organism:
Phaeodactylum tricornutum CCAP 1055/1
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33107
24 Samples
Download data: XLSX
Series
Accession:
GSE224880
ID:
200224880

2.

Anylasis of the diatom Phaeodactylum tricornutum under 64-75-5,Tetracycline hydrochloride stress

(Submitter supplied) Anylasis of the diatom Phaeodactylum tricornutum under 64-75-5,Tetracycline hydrochloride stress
Organism:
Phaeodactylum tricornutum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19904
6 Samples
Download data: TXT
Series
Accession:
GSE218473
ID:
200218473

3.

Evolutionary and functional analysis of DNA methyltransferases in micro-eukaryotes: Insights from the model diatom Phaeodactylum tricornutum

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Phaeodactylum tricornutum
Type:
Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platform:
GPL30913
9 Samples
Download data: BW, TSV
Series
Accession:
GSE186857
ID:
200186857

PubMed Full text in PMC Similar studies

4.

Evolutionary and functional analysis of DNA methyltransferases in micro-eukaryotes: Insights from the model diatom Phaeodactylum tricornutum [RNA-seq]

(Submitter supplied) Loss of DNA methylation is traditionally associated with transcriptional up-regulation of transposable elements. Here we describe for the first time expression changes upon loss of DNA methylation in diatoms using Phaeodactylum tricornutum as a model species. The loss of DNA methylation was obtained by generation of DNMT5 KOs, a divergent DNMT with SNF-like domains. Expression analysis confirm the loss of DNA methylation is associated with de-repression of transposable elements in Phaeodactylum tricornutum with indirect effects on protein coding genes.
Organism:
Phaeodactylum tricornutum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30913
6 Samples
Download data: TSV
Series
Accession:
GSE186856
ID:
200186856

PubMed Full text in PMC Similar studies SRA Run Selector

5.

Evolutionary and functional analysis of DNA methyltransferases in micro-eukaryotes: Insights from the model diatom Phaeodactylum tricornutum [Bisulfite-Seq]

(Submitter supplied) DNA methylation has been associated with transcriptional repression of transposable elements. Here we describe the first DNA methylation deficient cell line of a diatom by generating DNMT5:KOs in Phaeodactylum tricornutum. These data show the extend of the loss of DNA methylation in DNMT5:KOs compared to the reference strain. All DNA methylation is lost in DNMT5:KOs.
Organism:
Phaeodactylum tricornutum
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL30913
3 Samples
Download data: BW
Series
Accession:
GSE186855
ID:
200186855

PubMed Full text in PMC Similar studies SRA Run Selector

6.

Hypometabolism to survive the long polar night in the diatom Fragilariopsis cylindrus

(Submitter supplied) Diatoms, the major eukaryotic phytoplankton in polar regions, are essential to sustain food webs. As such, it is fundamental to understand the physiological mechanisms and associated molecular basis of resilience to polar night of diatoms. Here, we report an integrative approach that reveals that in prolonged darkness, the cell enters a state of hypometabolism associated with reduced transcriptional activity during which no cell division occurs. more...
Organism:
Fragilariopsis cylindrus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32861
66 Samples
Download data: XLSX
Series
Accession:
GSE218215
ID:
200218215

7.

Five diatoms transcriptomes under iron limitation and oxidative stress

(Submitter supplied) Divergent functions of two clades of flavodoxin in diatoms mitigate oxidative stress and iron limitation Thalassiosira pseudonana and 4 open-ocean diatoms were subjected to iron limitation or short-term oxidative stress (hydrogen peroxide). mRNA profiles of T. pseudonana (CCMP1335), Thalassiosira oceanica (CCMP1005), Amphora coffeaeformis (CCMP1405), Chaetoceros sp. (CCMP199), and Cylindrotheca closterium (CCMP340).
Organism:
Amphora coffeiformis; Thalassiosira pseudonana; Chaetoceros sp. CCMP199; Thalassiosira oceanica; Cylindrotheca closterium
Type:
Expression profiling by high throughput sequencing
5 related Platforms
37 Samples
Download data: CSV, FASTA
Series
Accession:
GSE217467
ID:
200217467

PubMed Full text in PMC Similar studies

8.

Analysis of the α-1,3 fucosyltransferase gene funtion in diatom Phaeodactylum tricornutum

(Submitter supplied) Anylasis of the α-1,3 fucosyltransferase gene function in diatom Phaeodactylum tricornutum
Organism:
Phaeodactylum tricornutum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19904
9 Samples
Download data: TXT
Series
Accession:
GSE214570
ID:
200214570

9.

Regulatory mechanism of diurnal fluctuated laminarin in diatom Phaeodactylum tricornutum

(Submitter supplied) Diatoms played an essential role in marine primary productivity. Polysaccharide chrysolaminarin and neutral lipid, mainly TAG, were necessary carbon fixation in diatom Phaeodactylum tricornutum. Our study speculated on the metabolism pathway of chrysolaminarin, fatty acid, fatty acid β-oxidation and TAG. Transcriptional levels coordinated with carbon fixation metabolism pathway were conjoint analysis in this study. 
Organism:
Phaeodactylum tricornutum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19904
21 Samples
Download data: TXT
Series
Accession:
GSE210141
ID:
200210141

10.

Tunicamycin-induced Endoplasmic Reticulum-Quality Control Pathway and Endoplasmic Reticulum-Associated Degradation Mechanism in the diatom Phaeodactylum tricornutum

(Submitter supplied) Tunicamycin inhibits the first step of protein N-glycosylation modification. However, the physiological, transcriptomic, and N-glycomic effects of tunicamycin on important marine diatom Phaeodactylum tricornutum are still unknown. In this study, comprehensive approaches were used to study the effects. The results showed that cell growth and photosynthesis were significantly inhibited in P. tricornutum under the tunicamycin stress. more...
Organism:
Phaeodactylum tricornutum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19904
6 Samples
Download data: TXT
Series
Accession:
GSE209809
ID:
200209809

11.

Flavobacterial exudates disrupt cell cycle progression and metabolism of the diatom Thalassiosira pseudonana

(Submitter supplied) Phytoplankton and bacteria form the base of marine ecosystems and their interactions drive global biogeochemical cycles. The effect of bacteria and bacteria-produced compounds on diatoms range from synergistic to pathogenic and can affect the physiology and transcriptional patterns of the interacting diatom. Here, we investigate physiological and transcriptional changes in the marine diatom Thalassiosira pseudonana induced by extracellular metabolites of a known antagonistic bacterium Croceibacter atlanticus. more...
Organism:
Thalassiosira pseudonana
Type:
Expression profiling by high throughput sequencing
Platform:
GPL29842
24 Samples
Download data: CSV
Series
Accession:
GSE197934
ID:
200197934

12.

The dynamic response to hypoosmotic stress reveals distinct stages of freshwater acclimation by a euryhaline diatom

(Submitter supplied) The salinity gradient separating marine and freshwater environments is a major ecological divide, and the mechanisms by which most organisms adapt to new salinity environments are poorly understood. Diatoms are a lineage of ancestrally marine microalgae that have repeatedly colonized and diversified in freshwaters. Cyclotella cryptica is a euryhaline diatom that naturally tolerates a broad range of salinities, thus providing a powerful system for understanding the genomic mechanisms for mitigating and acclimating to low salinity. more...
Organism:
Cyclotella cryptica
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32380
27 Samples
Download data: TXT
Series
Accession:
GSE206725
ID:
200206725

PubMed Similar studies

13.

Quantitative Analysis of Phaeodactylum tricornutum transcriptomes

(Submitter supplied) Purpose: Using RNAseq to profile transcriptomes to compare wildtype and PtTryp2 knockout lines across different nutrient conditions, aim to further explore the molecular function of PtTryp2 in regulating cell growth and responses to N- and P-stress. Methods: Libraries for RNAseq were created from 1µg of mRNA from each culture. The resulting libraries were loaded into the patterned nanoarray, and single-end 50 bp reads were generated on BGIseq500 platform (BGI-Shenzhen, China), with a data output of about 22 M total clean reads for each library. more...
Organism:
Phaeodactylum tricornutum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32251
18 Samples
Download data: RESULTS
Series
Accession:
GSE202896
ID:
200202896

PubMed Full text in PMC Similar studies

14.

Synchronous cell cycle progression in the diatom Thalassiosira pseudonana

(Submitter supplied) To identify the molecular components involved in diatom cell division, global transcript level changes were monitored over the silicon-synchronized cell cycle the model diatom Thalassiosira pseudonana.
Organism:
Thalassiosira pseudonana CCMP1335
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16011
20 Samples
Download data: CSV
Series
Accession:
GSE203136
ID:
200203136

15.

Transcriptomic profiling of an oceanic diatom adapted to Cu deficiency

(Submitter supplied) Enhanced vertical stratification brought about by warming of the ocean surface is expected to reduce vertical circulation and nutrient input with knock-on effects for phytoplankton. Increased nutrient limitation is one predicted outcome, but the response of phytoplankton is uncertain because long-term adaptation to nutrient limitation has not been studied. We used Cu as a model catalytic nutrient to explore the adaptive response of an oceanic diatom to continuous nutrient deprivation. more...
Organism:
Thalassiosira oceanica CCMP1005
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30969
6 Samples
Download data: FASTA, TXT
Series
Accession:
GSE188999
ID:
200188999

SRA Run Selector

16.

Thermal transcriptome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Synechocystis sp. PCC 6803; Phaeodactylum tricornutum
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24784 GPL28944
188 Samples
Download data: TXT
Series
Accession:
GSE186039
ID:
200186039

17.

Thermal transcriptome of Phaeodactylum tricornutum in steady-state growth

(Submitter supplied) Here we use a transcriptomic approach to investigate the molecular underpinnings of thermal acclimation in the model diatom species Phaeodactylum tricornutum by comparing the differential gene expression in cultures acclimated to sub-optimal, optimal, and supra-optimal temperatures (10, 20 and 26.5 °C, respectively).
Organism:
Phaeodactylum tricornutum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24784
12 Samples
Download data: TXT
Series
Accession:
GSE186035
ID:
200186035

SRA Run Selector

18.

Thermal transcriptome of Phaeodactylum tricornutum in response to gradual heat stress

(Submitter supplied) Here we use a transcriptomic approach to investigate the molecular underpinnings of thermal stress in the model diatom species Phaeodactylum tricornutum. We expose cultures to high temperature (optimal +8°C) and follow changes in gene expression through time (over a 12 hour period) in comparison to optimal conditions (20 °C).
Organism:
Phaeodactylum tricornutum
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24784
104 Samples
Download data: TXT
Series
Accession:
GSE186033
ID:
200186033

SRA Run Selector

19.

Transcriptomic analysis of the marine diatom Nitzschia laevis during glucose-induced trophic transition

(Submitter supplied) RNA sequencing (RNA-seq) experiment was performed on 18 samples of Nitzschia laevis cells collected at 3 h, 6 h and 12 h after inoculation in treated medium with glucose addition (+G) and control group (-G) respectively. The de novo assembly totally generated 16650 unigenes.
Organism:
Nitzschia laevis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL29856
18 Samples
Download data: FASTA, XLSX
Series
Accession:
GSE168959
ID:
200168959

PubMed Full text in PMC Similar studies SRA Run Selector

20.

The diatom Thalassiosira pseudonana grown in mesocosms at contemporary and elevated CO2 over the diel cycle

(Submitter supplied) To test whether elevated CO2 , which drives seawater below pH 7.9, would shift the dynamical expression patterns diatoms in a more natural environment, we designed a controlled mesocosm study at Friday Harbor Laboratories (FHL) Ocean Acidification Environmental Laboratory (OAEL). Briefly, four independent mesocosm tanks were set up with continuous flow (10-12 mL/min) of filtered seawater from the Puget Sound to simulate mid-century (pH 7.9) and acidified oceanic conditions (pH 7.6) in duplicate. more...
Organism:
Thalassiosira pseudonana
Type:
Expression profiling by high throughput sequencing
Platform:
GPL29842
16 Samples
Download data: TXT
Series
Accession:
GSE168812
ID:
200168812

SRA Run Selector

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filters: Manage Filters

db=gds|term=txid2836[Organism:exp]|query=9|qty=60|blobid=MCID_67266c038779bd4d7b2fcf34|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Important Links

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets
Support Center