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Changes in gene expression in the retina of diabetic Long Evans rats after one, four, and twelve weeks of diabetes

(Submitter supplied) Purpose. Patients with diabetic retinopathy may experience severe vision loss due to macular edema and neovascularization secondary to vascular abnormalities. However, before these abnormalities become apparent, there are functional deficits in contrast sensitivity, color perception, and dark adaptation. The goals of this study are to evaluate early changes (up to 3 months) in retinal gene expression, selected visual cycle proteins, and optokinetic tracking (OKT) in streptozotocin (STZ)-induced diabetic rats.Methods. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL7294
21 Samples
Download data: TXT
Series
Accession:
GSE28831
ID:
200028831

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