arc3[All Fields] AND 1[has_clinical] - GEO DataSets

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Items: 10

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Select item 2002417671.

Epigenome analysis of anterior capsular membrane of lens in healthy and cataract patients

(Submitter supplied) DNA methylation levels were analyzed by MethylationEPIC BeadChip (850K) in ARC patients and normal controls. Compared with the control group, a total of 52705 differentially methylated site (DMS) were detected in the ARC group, of which 13858 were hypermethylated and 38847 were hypomethylated. Our study revealed that the whole-genome DNA methylation patterns and gene expression profiles in ARC and identifified molecular markers of methylation may aid in the prevention, diagnosis, treatment, and prognosis of ARC.

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL23976
6 Samples

Download data: IDAT, XLSX

Series

Accession:: GSE241767

ID:: 200241767

Analyze with GEO2R

Select item 2000933742.

A Molecular Census of Arcuate Hypothalamus and Median Eminence Cell Types

(Submitter supplied) Drop-seq and single cell sequencing of mouse arcuate nucleus and median eminence. Please see below link for searchable cluster-based gene expression.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19057
11 Samples

Download data: TXT

Series

Accession:: GSE93374

ID:: 200093374

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000303653.

Transcript Profiling of Arcuate Nucleus in Response to Electroacupuncture on Rats

(Submitter supplied) The electroacupuncture-induced analgesic effect has been used widely to alleviate diverse pains. However, significant individual variations in analgesic effect of EA for both experiments and clinics were reported. According to the sensitivity of the analgesic response to EA stimulation, the subjects could be categorized into high responders (HR) and non responders (NR). However, the molecular mechanism of individual variability in the analgesic response to acupuncture stimulation is still uncertain. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL3498
12 Samples

Download data: TXT

Series

Accession:: GSE30365

ID:: 200030365

Select item 2000174304.

Transcript Profiling of Different CNS Regions in Response to Experimental Restraint Stress on Rats

(Submitter supplied) It generally believes that moderate stress could have protective and adaptive effects, but less is known about the moderate or experimental stress on CNS in stimulated animals. This study aims to investigate the potential gene expression in nociception-related central regions induced by moderate experimental stress in rats. Rats were given moderate restrain for 50 min and using cDNA microarrays to compare different gene expression in central regions. more...