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Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity

(Submitter supplied) The DNA sequence preferences of the vast majority of eukaryotic transcription factors (TFs) are unknown. Using an approach designed to broadly sample both DNA-binding domain types and eukaryotic clades, we have determined DNA-binding motifs for 1,033 TFs from 131 diverse eukaryotes, encompassing 54 domain types. Closely related orthologs and paralogs typically have very similar sequence preferences; this property allows inference of motifs for roughly one third of the 166,851 known or predicted eukaryotic TFs. more...
Organism:
synthetic construct
Type:
Other
Platform:
GPL11260
2064 Samples
Download data: TXT
Series
Accession:
GSE53348
ID:
200053348

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