Mir29b[All Fields] AND 1[has_clinical] - GEO DataSets

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Items: 11

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Select item 2001204611.

ROR1-targeted delivery of miR-29b results in epigenetic reprogramming with p21-dependent cell cycle arrest

(Submitter supplied) RNAseq analysis of purified splenic CD19+ B lymphocytes from the hRORxTCL1 mouse model treated with 2A2-miR-29b-ILP or 2A2-scramble-ILP. Moreover, 128 of the 233 differentially expressed genes are related to cell growth and proliferation.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17021
11 Samples

Download data: TSV

Series

Accession:: GSE120461

ID:: 200120461

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001223522.

Real-time quantitative PCR analysis of human exosomes

(Submitter supplied) Paroxysmal Nocturnal Hemoglobinuria (PNH) is a clonal disease of blood cells caused by the lack of glycosyl phosphatidyl inositol anchored proteins bound to the cell membrane. In consequence, erythrocytes lead to intravascular hemolysis upon complement activation, which promotes high risk of thrombosis, intravascular hemolytic anemia, and bone marrow failure in patients. The mechanisms of thrombosis in PNH are still poorly understood. more...

Organism:: Homo sapiens

Type:: Expression profiling by RT-PCR

Platform:: GPL25788
12 Samples

Download data: TXT

Series

Accession:: GSE122352

ID:: 200122352

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001232933.

Expression data from lung tissue of Zmpste24 defient or wildtype c57BL/6 mice

(Submitter supplied) Idiopathic pulmonary fibrosis is a devastating aging-associated disease of unknown etiology. Despite that aging is a major risk factor, the mechanisms linking aging with this disease are uncertain, and experimental models to explore them in lung fibrosis are scanty. We examined the fibrotic response to bleomycin-induced lung injury in Zmpste24-deficient mice, which exhibit nuclear lamina defects developing accelerated aging. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL16570
30 Samples

Download data: CEL

Series

Accession:: GSE123293

ID:: 200123293

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000447844.

miR-29 affect on DC gene expression

(Submitter supplied) Transcriptional profiling of human monocyte-derived dendritic cells (MDDCs), comparing cells transfected with miR-29a mimic, or miR-29b mimic, or negative control.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
6 Samples

Download data: TXT

Series

Accession:: GSE44784

ID:: 200044784

Select item 2000187135.

Changes in gene expression induced by miR29b in HTM cells

(Submitter supplied) To investigate the role of miR-29b on the changes in expression of genes involved in the synthesis and deposition of extracellular matrix in human trabecular meshwork cells (HTM).