4-phenylbutyrate treatment prevents amyloid formation and restores β-cell function in mice overexpressing human islet amyloid polypeptide. - - GEO DataSets

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4-phenylbutyrate treatment prevents amyloid formation and restores β-cell function in mice overexpressing human islet amyloid polypeptide.

(Submitter supplied) 4-phenylbutyrate (PBA) is a chemical chaperone that has been shown to ameliorate β-cell dysfunction associated with hIAPP overexpression. The aim of the study was to investigate the in vivo effects of PBA in transgenic mice overexpressing hIAPP. We used microarrays to determine gene expression changes in pancreatic islets from mice overexepressing hIAPP and treated with PBA during 12 weeks.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11180
8 Samples

Download data: CEL

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Accession:: GSE84423

ID:: 200084423

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Did you mean: j bach (7 items)

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4-phenylbutyrate treatment prevents amyloid formation and restores β-cell functi...
4-phenylbutyrate treatment prevents amyloid formation and restores β-cell function in mice overexpressing human islet amyloid polypeptide.
Accession: GSE84423

GEO DataSets
J Obach (1)
GEO DataSets
Homo sapiens FERM and PDZ domain containing 2 like 2, mRNA (cDNA clone MGC:17818...
Homo sapiens FERM and PDZ domain containing 2 like 2, mRNA (cDNA clone MGC:178184 IMAGE:9053167), complete cds
gi|219519167|gb|BC144636.1|

Nucleotide

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