GSM997572[Accession] - GEO DataSets

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Items: 4

Select item 2000405931.

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells

(Submitter supplied) In the course of primary infection with herpes simplex virus 1 (HSV-1), children with inborn errors of the TLR3- and UNC-93B-dependent induction of IFN-α/β and/or IFN-λ immunity are prone to HSV-1 encephalitis (HSE) 1-3. The cells responsible for HSE in these children have yet to be identified. We tested the hypothesis that the pathogenesis of HSE involves non hematopoietic central nervous system (CNS)-resident cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS4538 GDS4669
Platform:: GPL6884
18 Samples

Download data: TXT

Series

Accession:: GSE40593

ID:: 200040593

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 46692.

Central nervous system cell types derived from UNC-93B-deficient induced pluripotent stem cells

Analysis of neurons and astrocytes derived from UNC-93B-deficient induced pluripotent stem cells (UNC93B-/- iPS) and from hESCs (H9). UNC-93B-/- neurons are highly susceptible to herpes simplex virus 1 (HSV-1) infection. Results provide insight into role of neurons in anti-HSV-1 immunity in the CNS.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell line, 3 cell type sets

Platform:: GPL6884
Series:: GSE40593
13 Samples

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DataSet

Accession:: GDS4669

ID:: 4669

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000068843.

Illumina HumanWG-6 v3.0 expression beadchip

(Submitter supplied) The HumanWG-6 v3.0 Expression BeadChip features up-to-date content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36.2, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. These should be submitted as part of a GEOarchive. more...