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Items: 4

1.

Vascular histone deacetylation by pharmacological HDAC inhibition

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below. HDAC inhibitors are thought to regulate gene expression by post-translational modification of histone as well as non-histone proteins. Often studied at single loci, increased histone acetylation is the paradigmatic mechanism of action, however, little is known of the extent of genome-wide changes of the mammalian genome when stimulated by the hydroxamic acids, TSA and SAHA. more...
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL11002 GPL10999
65 Samples
Download data: BED
Series
Accession:
GSE37378
ID:
200037378

PubMed Full text in PMC Similar studies

2.

Vascular histone deacetylation by pharmacological HDAC inhibition [TSA, ChIP-seq]

(Submitter supplied) HDAC inhibitors are thought to regulate gene expression by post-translational modification of histone as well as non-histone proteins. Often studied at single loci, increased histone acetylation is the paradigmatic mechanism of action, however, little is known of the extent of genome-wide changes of the mammalian genome when stimulated by the hydroxamic acids, TSA and SAHA. In primary human vascular endothelial cells we map the chromatin modifications, histone H3 acetylation of lysine 9 and 14 (H3K9/14ac) using chromatin immunoprecipitation (ChIP) coupled with massive parallel sequencing (ChIP-seq). more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL10999
21 Samples
Download data: BED
Series
Accession:
GSE37377
ID:
200037377

PubMed Full text in PMC Similar studies SRA Run Selector

3.

Illumina Genome Analyzer IIx (Homo sapiens)

Organism:
Homo sapiens
1102 Series
10066 Samples
Download data
Platform
Accession:
GPL10999
ID:
100010999

4.

HAEC H3K4Me3 TSA1

Organism:
Homo sapiens
Source name:
HAEC_H3K4Me3_500nM TSA_12h
Platform:
GPL10999
Series:
GSE37377 GSE37378
Download data: BED
Sample
Accession:
GSM916975
ID:
300916975

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db=gds|term=GSM916975[Accession]|query=14|qty=3|blobid=MCID_6737a981bea12f4e7c7aa543|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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