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Items: 3

1.

Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes.

(Submitter supplied) Signal Transducers and Activators of Transcription (STAT) 5A/B regulate cytokine-inducible genes upon binding to GAS motifs. It is not known what percentage of genes with GAS motifs bind to and are regulated by STAT5. Moreover, it is not clear whether genome-wide STAT5 binding is modulated by its concentration. To clarify these issues we established genome-wide STAT5 binding upon growth hormone (GH) stimulation of wild type mouse embryonic fibroblasts (MEFs) and MEFs overexpressing STAT5A more than 20-fold. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13112
12 Samples
Download data: BED, BEDGRAPH
Series
Accession:
GSE34986
ID:
200034986
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

MEF_STAT5-KO-empty-GH-IgG

Organism:
Mus musculus
Source name:
MEF_STAT5-KO-empty-GH-IgG
Platform:
GPL13112
Series:
GSE34986
Download data
Sample
Accession:
GSM860159
ID:
300860159
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db=gds|term=GSM860159[Accession]|query=1|qty=2|blobid=MCID_66373ace679af6518b8addc9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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