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Items: 3

1.

Identifying new cellular mechanisms of MCPH5

(Submitter supplied) The coordination of cellular behaviors during neurodevelopment is critical for determining the form, function, and size of the central nervous system. Mutations in the vertebrate Abnormal Spindle-Like, Microcephaly Associated (ASPM) gene and its Drosophila melanogaster ortholog abnormal spindle (asp) lead to microcephaly, a reduction in overall brain size whose etiology remains poorly defined. Here we provide the neurodevelopmental transcriptional landscape for a Drosophila model for autosomal recessive primary microcephaly-5 (MCPH5) and extend our findings into the functional realm to identify the key cellular mechanisms responsible for Asp-dependent brain growth and development. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25244
36 Samples
Download data: TXT
Series
Accession:
GSE244463
ID:
200244463

PubMed Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Drosophila melanogaster)

Organism:
Drosophila melanogaster
801 Series
29960 Samples
Download data
Platform
Accession:
GPL25244
ID:
100025244

3.

Adult Brain, Rescue, Rep. 1

Organism:
Drosophila melanogaster
Source name:
Brain
Platform:
GPL25244
Series:
GSE244463
Download data: TXT
Sample
Accession:
GSM7816427
ID:
307816427

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db=gds|term=GSM7816427[Accession]|query=34|qty=2|blobid=MCID_673190baf73b361c51523450|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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