GSM747543[Accession] - GEO DataSets

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Items: 4

Select item 2000302061.

DNA binding factors shape the mouse methylome at distal regulatory regions.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Genome binding/occupancy profiling by array; Expression profiling by high throughput sequencing

Platforms:: GPL13112 GPL11002 GPL13253
23 Samples

Download data: PAIR, WIG

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Accession:: GSE30206

ID:: 200030206

Select item 2000302032.

DNA binding factors shape the mouse methylome at distal regulatory regions [ChIP-seq].

(Submitter supplied) To gain insights into the interplay between DNA methylation and gene regulation we generated a basepair resolution reference map of the mouse methylome in stem cells and neurons. High genome coverage allowed for a novel quantitative analysis of local methylation states, which identified Low Methylated Regions (LMR) with an average methylation of 30%. These regions are evolutionary conserved, reside outside of CpG islands and distal to promoters. more...