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Items: 3

1.

Splicing targeting approaches highlight actionable vulnerabilities in advanced prostate cancer [22Rv1]

(Submitter supplied) To investigate if pharmacological inhibition of splicing could uncover novel actionable vulnerabilities in CRPC, we profiled the genome-wide transcriptional changes elicited in 22Rv1 cells by treatment with three drugs that inhibit the splicing through different molecular targets: i. Pladienolide B, that impairs the activity of SF3B1; ii. Indisulam that promote degradation of the splicing factor RBM39; iii. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
12 Samples
Download data: TXT
Series
Accession:
GSE234734
ID:
200234734

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
17145 Series
934634 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

22Rv1 THZ531 treated replica 2

Organism:
Homo sapiens
Source name:
22Rv7
Platform:
GPL24676
Series:
GSE234734
Download data
Sample
Accession:
GSM7474036
ID:
307474036

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db=gds|term=GSM7474036[Accession]|query=2|qty=2|blobid=MCID_673a88c27405eb4f274bf71b|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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