GSM7440494[Accession] - GEO DataSets

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Items: 4

Select item 2002340101.

Improved RNA stability estimation through Bayesian modeling reveals most Salmonella transcripts have subminute half-lives

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Salmonella enterica subsp. enterica serovar Typhimurium

Type:: Other; Expression profiling by high throughput sequencing

Platforms:: GPL21220 GPL17070
132 Samples

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Accession:: GSE234010

ID:: 200234010

PubMed Full text in PMC Similar studies

Select item 2002340092.

Improved RNA stability estimation through Bayesian modeling reveals most bacterial transcripts have sub-minute half-lives [RIF-seq]

(Submitter supplied) RNA decay is a crucial mechanism for regulating gene expression in response to environmental stresses. In bacteria, RNA-binding proteins (RBPs) are known to be involved in post-transcriptional regulation, but their global impact on RNA half-lives has not been extensively studied. To shed light on the role of the major RBPs ProQ and CspC/E in maintaining RNA stability, we performed RNA sequencing of Salmonella enterica over a time course following treatment with the transcription initiation inhibitor rifampicin (RIF-seq) in the presence and absence of these RBPs. more...