GSM7113518[Accession] - GEO DataSets

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Items: 4

Select item 2002281421.

Linker histone H1 regulates homeostasis of heterochromatin associated cRNAs

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Drosophila melanogaster

Type:: Other; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL25244
48 Samples

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Accession:: GSE228142

ID:: 200228142

PubMed Similar studies

Select item 2002280682.

Linker histone H1 regulates homeostasis of heterochromatin associated cRNAs [ChIP-seq 2]

(Submitter supplied) Chromosomal RNAs (cRNAs) are a poorly understood fraction of cellular RNAs that co-purify with chromatin. Here we show that, in Drosophila, cRNAs constitute a heterogeneous group of RNA species that cover ~28% of the genome. Intriguingly, we found that cRNAs are highly enriched in heterochromatic transcripts. Our results show that heterochromatic cRNAs interact with the hnRNP A/B proteins hrp36 and hrp48 to assemble into RNP particles. more...