GSM5662441[Accession] - GEO DataSets

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Items: 4

Select item 2001868591.

Genome-Wide Host Methylation Profiling of Anal and Cervical Carcinoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
171 Samples

Download data: IDAT

Series

Accession:: GSE186859

ID:: 200186859

Analyze with GEO2R

Select item 2001868582.

Genome-Wide Host Methylation Profiling of Anal and Cervical Carcinoma [anal]

(Submitter supplied) HPV infection results in changes in host gene methylation which, in turn, are thought to contribute to the neoplastic progression of HPV-associated cancers. The objective of this study was to identify joint and disease-specific genome-wide methylation changes in anal and cervical cancer as well as changes in high-grade pre-neoplastic lesions. Formalin-fixed paraffin-embedded (FFPE) anal tissues (n=143; 99% HPV+) and fresh frozen cervical tissues (n=28; 100% HPV+) underwent microdissection, DNA extraction, HPV genotyping, bisulfite modification, DNA restoration (FFPE) and analysis by the Illumina HumanMethylation450 Array.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
143 Samples

Download data: IDAT

Series

Accession:: GSE186858

ID:: 200186858

Analyze with GEO2R

Select item 1000135343.

Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)

(Submitter supplied) 1 difference between HumanMethylation450_15017482_v.1.1.bpm and HumanMethylation450_15017482_v.1.2.bpm: 1.1: 41636384,NEGATIVE,-99,Negative 604 1.2: 41636384,RESTORATION,Green,Restore Protocol: See manufacturer's website