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Items: 3

1.

RNA surveillance and the periphery: a novel role for nuclear envelope protein Lem2 

(Submitter supplied) Transcriptionally silent chromatin often localizes at the nuclear periphery, but whether post-transcriptional gene repression also occurs at the nuclear envelope (NE) remains unknown. Here we demonstrate that the NE protein Lem2 cooperates with the nuclear exosome in RNA degradation. Loss of Lem2 causes the accumulation of non-coding RNAs and meiotic transcripts. We demonstrate that an engineered exosome RNA substrate preferentially localizes at the nuclear periphery dependent on Lem2. more...
Organism:
Schizosaccharomyces pombe
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL30658 GPL22681
47 Samples
Download data: BEDGRAPH
Series
Accession:
GSE174347
ID:
200174347
2.

NextSeq 2000 (Schizosaccharomyces pombe)

Organism:
Schizosaccharomyces pombe
6 Series
221 Samples
Download data
Platform
Accession:
GPL30658
ID:
100030658
3.

lem2iss10_RNA-seq_rep3

Organism:
Schizosaccharomyces pombe
Source name:
logarithmically growing lem2-deltaiss10-delta cells
Platform:
GPL30658
Series:
GSE174347
Download data: BEDGRAPH
Sample
Accession:
GSM5592478
ID:
305592478
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db=gds|term=GSM5592478[Accession]|query=7|qty=2|blobid=MCID_67148a2684112c3be2532ab9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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