GSM5455448[Accession] - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Search results

Items: 4

Select item 2001442461.

m6A RNA methylation regulates promoter proximal pausing of RNA Pol II

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Drosophila melanogaster

Type:: Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL25244 GPL19132
68 Samples

Download data

Series

Accession:: GSE144246

ID:: 200144246

PubMed Similar studies

Select item 2001442452.

m6A RNA methylation regulates promoter proximal pausing of RNA Pol II (DRB-4sU-seq)

(Submitter supplied) RNA modification has emerged as an important layer in the control of gene expression. The N6-methyladenosine (m6A) RNA modification is the most prevalent and influences several processes including pre-mRNA splicing, alternative polyadenylation, mRNA decay and translation. Here, we show that m6A regulates transcription by controlling promoter proximal pause release of RNA Pol II. Our results show that the m6A methyltransferase complex together with the nuclear reader Ythdc1 are recruited to gene promoters. more...