GSM5277463[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2001737231.

Impaired GR expression in liver disrupts feeding induced gene expression, glucose uptake and glycogen storage

(Submitter supplied) The transition from a fasted to a fed state is associated with extensive transcriptional remodeling in hepatocytes facilitated by hormonal- and nutritional-regulated transcription factors. Here, we use a liver-specific glucocorticoid receptor (GR) knock-out (L-GRKO) model and primary hepatocytes to investigate the temporal expression of GR target genes in response to feeding. Interestingly, in addition to the well described fasting-regulated genes, we identify a subset of hepatic feeding-induced genes that requires GR for full expression, adding new insights to hepatic GR function. more...

Organism:: Mus musculus; Rattus norvegicus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL18404 GPL24247 GPL18480
79 Samples

Download data: BEDGRAPH, TXT

Series

Accession:: GSE173723

ID:: 200173723

PubMed Similar studies SRA Run Selector

Select item 1000184042.

Illumina HiSeq 1500 (Rattus norvegicus)

Organism:: Rattus norvegicus

17 Series
268 Samples

Platform

Accession:: GPL18404

ID:: 100018404

Select item 3052774633.

Organism:: Rattus norvegicus

Source name:: primary hepatocyte

Platform:: GPL18404
Series:: GSE173723

Sample

Accession:: GSM5277463

ID:: 305277463

SRA Run Selector

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GSM5277463[Accession] (3)
GEO DataSets
221858[uid] (1)
Taxonomy
PREDICTED: Zea mays uncharacterized LOC100216569 (LOC100216569), transcript vari...
PREDICTED: Zea mays uncharacterized LOC100216569 (LOC100216569), transcript variant X2, mRNA
gi|1898150318|ref|XM_035962076.1|

Nucleotide
Vibrio gigantis strain BBCC2412 16S ribosomal RNA gene, partial sequence
Vibrio gigantis strain BBCC2412 16S ribosomal RNA gene, partial sequence
gi|1153219940|gb|KY697686.1|

Nucleotide
Vibrio mytili strain BBCC2428 16S ribosomal RNA gene, partial sequence
Vibrio mytili strain BBCC2428 16S ribosomal RNA gene, partial sequence
gi|1153219943|gb|KY697689.1|

Nucleotide

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