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Items: 4

1.

Selumetinib

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome variation profiling by SNP array; SNP genotyping by SNP array
Platforms:
GPL19718 GPL18573 GPL16791
133 Samples
Download data: IDAT
Series
Accession:
GSE168604
ID:
200168604
2.

Gene expression profiling during treatment of COLO205 cells with selumetinib

(Submitter supplied) Here, we investigate gene expression response of the BRAFV600E mutant cell line COLO205 to the MEK inhibitor selumetinib / AZD6244 / ARRY-142886. Although selumetinib causes long term G1 arrest, we observe cells stochastically entering the cell cycle without re-activation of ERK and initiation of a normal proliferative gene expression programme. Genes encoding DNA replication and repair factors are downregulated during G1 arrest, but many of these are transiently induced when cells escaping arrest enter S and G2. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
23 Samples
Download data: TXT
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

COLO205_untreated_2

Organism:
Homo sapiens
Source name:
COLO205
Platform:
GPL16791
Series:
GSE168602 GSE168604
Download data
Sample
Accession:
GSM5150550
ID:
305150550
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Supplemental Content

db=gds|term=GSM5150550[Accession]|query=13|qty=2|blobid=MCID_67322be9f73b361c5165a3ab|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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