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Items: 3

1.

Direct Formalin Fixation Induces Widespread Transcriptomic Effects in Archival Tissue Samples

(Submitter supplied) Archival formalin-fixed paraffin-embedded (FFPE) tissue samples hold a wealth of transcriptomic information; however, little is known about potential artifacts. Previously, we identified a consistent shift in global RNA-sequencing profiles between matching frozen and FFPE samples. We hypothesized that this shift was from fixing fresh tissue in formalin. To test this idea, RNA-sequencing was performed on liver samples collected from male mice treated with 600 ppm of a reference chemical (phenobarbital, 600 ppm phenobarbital) or vehicle control for 7 days. more...
Organism:
Rattus norvegicus; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21626 GPL17021 GPL25029
96 Samples
Download data: CSV, TXT
Series
Accession:
GSE148174
ID:
200148174

PubMed Full text in PMC Similar studies

2.

NextSeq 550 (Rattus norvegicus)

Organism:
Rattus norvegicus
52 Series
951 Samples
Download data
Platform
Accession:
GPL25029
ID:
100025029

3.

RNA-Rat-71

Organism:
Rattus norvegicus
Source name:
Liver
Platform:
GPL25029
Series:
GSE148174
Download data
Sample
Accession:
GSM4648373
ID:
304648373

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db=gds|term=GSM4648373[Accession]|query=2|qty=3|blobid=MCID_67070424c15063368055068d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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