GSM447258[Accession] - GEO DataSets

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Items: 3

Select item 2000179071.

Molecular profiling of ERBB2-amplified breast cancers

(Submitter supplied) 15-25% of breast cancers (BC) show ERBB2-amplification and overexpression of the encoded ERBB2 tyrosine kinase receptor. They are associated with a poor prognosis but can benefit from targeted therapy. A better knowledge of these BCs may help understand their behavior and design new therapeutic strategies. In this study, we defined the high resolution genome and gene expression profiles of 54 ERBB2-amplified BCs using 244K oligonucleotide array-comparative genomic hybridization and whole-genome DNA microarrays. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome variation profiling by array

Platforms:: GPL9128 GPL570
109 Samples

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Accession:: GSE17907

ID:: 200017907

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000091282.

Agilent-014693 Human Genome CGH Microarray 244A (Probe name version)

(Submitter supplied) This microarray is Agilent’s premium product for human DNA copy-number profiling. Over 236,000 60-mer oligonucleotide probes, specifically optimized for copy-number measurement, span coding and non-coding genomic sequences with median spacing of 7.4 kb and 16.5 kb respectively. This microarray is designed for use with Agilent’s optimized assay protocols, enabling researchers to use nanogram levels of total genomic DNA without complexity reduction. more...