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Items: 3

1.

Distinct epigenetic features of tumor-reactive CD8+ T cells in colorectal cancer patients revealed by genome-wide DNA methylation analysis

(Submitter supplied) Tumor-reactive CD8+ tumor infiltrating lymphocytes (TILs) represent a subtype of T cells that could recognize and destroy tumor specifically. Understanding the regulatory mechanism of tumor-reactive CD8+ T cells has important therapeutic implications. Yet the DNA methylation status of this T cell subtype has not been elucidated. In this study, we segregated tumor-reactive and bystander CD8+ TILs, as well as naïve and effector memory CD8+ T cell subtypes as controls from colorectal cancer (CRC) patients, to compare their transcriptome and methylome characteristics. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platform:
GPL24676
73 Samples
Download data: BED, CSV, TXT
Series
Accession:
GSE141878
ID:
200141878
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

RNA-seq: P1031_DP

Organism:
Homo sapiens
Source name:
CD103+ CD39+ (DP) T cells isolated from colorectal cancer patient
Platform:
GPL24676
Series:
GSE141878
Download data
Sample
Accession:
GSM4215320
ID:
304215320
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db=gds|term=GSM4215320[Accession]|query=1|qty=2|blobid=MCID_66299877f4364867153ff206|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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