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Items: 3

1.

Rheumatoid arthritis patients, both newly diagnosed and methotrexate treated, show more DNA methylation differences in CD4+ memory than in CD4+ naïve T cells

(Submitter supplied) Differences in DNA methylation have been reported in B and T lymphocyte populations, including CD4+ T cells, isolated from rheumatoid arthritis (RA) patients when compared to healthy controls. CD4+ T cells are a heterogeneous cell type with subpopulations displaying distinct DNA methylation patterns. In this study, we investigated DNA methylation using reduced representation bisulfite sequencing in two CD4+ T cell populations (CD4+ memory and naïve cells) in three groups: newly diagnosed, disease modifying antirheumatic drugs (DMARD) naïve RA patients (N=11), methotrexate (MTX) treated RA patients (N=18), and healthy controls (N=9) matched for age, gender and smoking status. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platforms:
GPL21290 GPL16791
94 Samples
Download data: BED
Series
Accession:
GSE135770
ID:
200135770
2.

Illumina HiSeq 3000 (Homo sapiens)

Platform
Accession:
GPL21290
ID:
100021290
3.

RA5103K3-4N: Newly diagnosed Rheumatoid Arthritis patient CD4nai 3.2

Organism:
Homo sapiens
Source name:
CD4+ naïve t cell
Platform:
GPL21290
Series:
GSE135770
Download data: BED
Sample
Accession:
GSM4029569
ID:
304029569
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db=gds|term=GSM4029569[Accession]|query=2|qty=2|blobid=MCID_672a3cd29a6e6010c1229ada|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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