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Items: 4

1.

CRISPR adenine and cytosine base editors with reduced RNA off-target activities

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL20301 GPL24676
61 Samples
Download data
Series
Accession:
GSE129894
ID:
200129894
2.

CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE]

(Submitter supplied) CRISPR-guided DNA base editors enable the efficient installation of targeted single-nucleotide changes. Cytosine or adenine base editors (CBEs or ABEs), which are fusions of cytidine or adenosine deaminases to CRISPR-Cas nickases, can efficiently induce DNA C-to-T or A-to-G alterations in DNA, respectively. We recently demonstrated that both the widely used CBE BE3 (harboring a rat APOBEC1 cytidine deaminase) and the optimized ABEmax editor can induce tens of thousands of guide RNA-independent, transcriptome-wide RNA base edits in human cells with high efficiencies. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
13 Samples
Download data: TSV
3.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
4.

HEK293T-GFP

Organism:
Homo sapiens
Source name:
HEK293T
Platform:
GPL20301
Series:
GSE129893 GSE129894
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Sample
Accession:
GSM3724622
ID:
303724622
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Supplemental Content

db=gds|term=GSM3724622[Accession]|query=6|qty=2|blobid=MCID_672f2bafb084802e7530264d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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