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Items: 4

1.

KLF4 binding is involved in the organization and regulation of 3D enhancer networks during acquisition and maintenance of pluripotency [ChIP-seq]

(Submitter supplied) Cell fate transitions are accompanied by global transcriptional, epigenetic and topological changes driven by transcription factors (TFs), as is strikingly exemplified in somatic cell reprogramming to pluripotent stem cells (PSCs) by OCT4, KLF4, SOX2 and cMYC. How TFs orchestrate the complex molecular changes around their targets in a temporal manner remains largely elusive. Here, using KLF4 as a paradigm, we provide the first TF-centric view of chromatin reorganization and the association to 3D enhancer rewiring and the transcriptional changes of linked genes during reprogramming of mouse embryonic fibroblasts to (MEFs) to PSCs. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17021
12 Samples
Download data: BED
Series
Accession:
GSE129494
ID:
200129494
2.

KLF4 binding is involved in the organization and regulation of 3D enhancer networks during acquisition and maintenance of pluripotency

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL17021 GPL21103
108 Samples
Download data: BED, BW, TXT
Series
Accession:
GSE113431
ID:
200113431
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

Input iPSC H3K27ac

Organism:
Mus musculus
Source name:
Induced Pluripotent Stem cells
Platform:
GPL17021
Series:
GSE113431 GSE129494
Download data
Sample
Accession:
GSM3714380
ID:
303714380
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Supplemental Content

db=gds|term=GSM3714380[Accession]|query=5|qty=2|blobid=MCID_672d4994fa580660f37354dd|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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