GSM347895[Accession] - GEO DataSets

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Items: 4

Select item 2000144281.

Physiological defects associated with short hairpin RNA-mediated silencing of PGC-1-related coactivator (PRC)

(Submitter supplied) PRC, a member of the PGC-1 coactivator family, is responsive to serum growth factors and up regulated in proliferating cells. Here, we investigated its in vivo role by stably silencing PRC expression with two different short hairpin RNAs (shRNA#1 and shRNA#4) that were lentivirally introduced into U2OS cells. ShRNA#1 transductants exhibited nearly complete knockdown of PRC protein whereas shRNA#4 transductants expressed PRC protein at approximately 15 percent of the control level. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS3531 GDS3532
Platform:: GPL6102
12 Samples

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Series

Accession:: GSE14428

ID:: 200014428

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 35312.

Analysis of U2OS cells partially depleted for the PGC-1-related coactivator PRC. Loss of PRC results in a severe reduction in respiratory energy production, the proliferation of structurally defective mitochondria, and a defect in cell cycle progression.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 protocol sets

Platform:: GPL6102
Series:: GSE14428
6 Samples

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DataSet

Accession:: GDS3531

ID:: 3531

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000061023.

Illumina human-6 v2.0 expression beadchip

(Submitter supplied) Researchers can generate whole genome expression profiles for multiple samples on a single BeadChip. Researchers can profile six or eight samples perBeadChip, with more than 48,000 transcript probes per sample using the Human-6 v2 beadchip. Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...