GSM3110333[Accession] - GEO DataSets

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Items: 4

Select item 2001136211.

Time series integrative analysis of RNA-Seq and miRNA expression data reveals key biologic pathways during keloid formation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array; Expression profiling by high throughput sequencing

Platforms:: GPL16791 GPL21290 GPL19117
91 Samples

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Accession:: GSE113621

ID:: 200113621

Select item 2001136192.

Time series integrative analysis of RNA-Seq and miRNA expression data reveals key biologic pathways during keloid formation [RNA-seq]

(Submitter supplied) Keloids represent a common form of exaggerated wound scarring that cause considerable morbidity. Moreover, there are limited data on molecular mechanisms underlying keloids and effective therapies are lacking. To gain new insight in the transcriptomic alterations of wound healing in keloid-prone individuals, we followed an integrative approach of RNA-Seq and miRNA expression data analysis in serial skin biopsies of the same site (baseline and six weeks after wounding) in keloid-prone (n=8) and healthy matched control individuals (n=6). more...