GEO DataSets

(Submitter supplied) The in vitro generation of neural crest (NC) cells from human pluripotent stem cells (hPSCs) is a valuable approach to study human NC biology and isolate NC derivatives for disease modelling/regenerative medicine applications. However, conventional differentiation protocols induce only a modest yield of NC cells corresponding to the trunk level. Here we show that trunk NC cells and, their downstream derivatives, sympathoadrenal progenitors, can be produced at a high efficiency from hPSC-derived axial progenitors, the in vitro counterparts of the posteriorly-located drivers of embryonic axis elongation. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL23126

21 Samples

Download data: CEL

(Submitter supplied) Annotation was derived from the Affymetrix annotation file Clariom_D_Human.na36.hg38.transcript.csv: #%create_date=Mon Jun 20 14:19:01 2016 PDT #%chip_type=Clariom_D_Human #%lib_set_name=Clariom_D_Human #%lib_set_version=r1 #%genome-species=Homo sapiens #%genome-version=hg38 #%genome-version-ucsc=hg38 #%genome-version-ncbi=GRCh38 #%genome-version-create_date=2013-12-00 #%genome-lifted-method=psl-map.pl #%genome-lifted_from-species=Homo sapiens #%genome-lifted_from-version-ucsc=hg38 #%genome-lifted_from-version-ncbi=GRCh38 #%netaffx-annotation-date=2016-06-03 #%netaffx-annotation-netaffx-build=36 Protocol: See manufacturers website

Organism:

Homo sapiens

272 Series

2 Related Platforms

5783 Samples

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