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Items: 3

1.

Enhancer connectome in primary human cells reveals target genes of disease-associated DNA elements

(Submitter supplied) The imprecision of linking intergenic mutations to target genes has limited molecular understanding of diverse human diseases. Here, we show H3K27ac HiChIP generates high-resolution contact maps of active enhancers and target genes in rare primary human T cell subtypes and coronary artery smooth muscle cells. Differentiation of naïve T cells to either T helper 17 cells or regulatory T cells create subtype-specific enhancer-promoter interactions, specifically at regions of shared DNA accessibility. more...
Organism:
Homo sapiens; Mus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL23787 GPL20301 GPL18573
58 Samples
Download data: BED, TXT
Series
Accession:
GSE101498
ID:
200101498

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 4000 (Homo sapiens)

Organism:
Homo sapiens
8450 Series
193310 Samples
Download data
Platform
Accession:
GPL20301
ID:
100020301

3.

K562 HiChIP H3K27ac biological replicate 2

Organism:
Homo sapiens
Source name:
K562 cell line
Platform:
GPL20301
Series:
GSE101498
Download data: TXT
Sample
Accession:
GSM2705044
ID:
302705044

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db=gds|term=GSM2705044[Accession]|query=5|qty=3|blobid=MCID_6716b29dd1cc6623eb2e7a85|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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