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Items: 3

1.

TRIM28 controls a gene regulatory network based on endogenous retroviruses in human neural progenitor cells

(Submitter supplied) Endogenous retroviruses (ERVs), which make up 8% of the human genome, have been proposed to participate in the control of gene regulatory networks. In this study, we find a region- and developmental stage-specific expression pattern of ERVs in the developing human brain, which is linked to a transcriptional network based on ERVs. We demonstrate that almost ten thousand, primarily primate-specific ERVs, act as docking platforms for the epigenetic co-repressor protein TRIM28 in human neural progenitor cells, which results in the establishment of local heterochromatin. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL21290 GPL16791
34 Samples
Download data: BED, TXT
Series
Accession:
GSE84259
ID:
200084259
2.

Illumina HiSeq 3000 (Homo sapiens)

Platform
Accession:
GPL21290
ID:
100021290
3.

TRIM28-KD_Sai-3

Organism:
Homo sapiens
Source name:
Sai cell culture
Platform:
GPL21290
Series:
GSE84259
Download data
Sample
Accession:
GSM2230408
ID:
302230408
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db=gds|term=GSM2230408[Accession]|query=1|qty=2|blobid=MCID_65db95b6a642ff6770ad95c0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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