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Items: 4

1.

Gene expression profiling in three primary human cell lines treated with atorvastatin or an inhibitor of Rho kinase

(Submitter supplied) Inhibitors of Rho kinase (ROCK) are a new class of drugs with potential benefit in oncology, neurology, and fibrotic and cardiovascular diseases. ROCK inhibitors modulate many cellular functions, some of which are similar to the pleiotropic (non-lipid lowering) effects of statins, suggesting additive or synergistic properties. Studies to date have used compounds which inhibit both isoforms of ROCK, ROCK1 and ROCK2. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2987
Platform:
GPL2507
36 Samples
Download data: TXT
Series
Accession:
GSE8686
ID:
200008686

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.
Full record GDS2987

Comparison of Rho kinase inhibitor and atorvastatin effects on primary cell lines

Analysis of three primary cell lines treated with Rho kinase (ROCK) 2 inhibitor SLx-2119 or with atorvastatin. Effects of ROCK inhibitors overlap to some extent with the pleiotropic (nonlipid lowering) effects of statins. Results suggest possible synergistic effects between the two classes of drugs.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 agent, 3 cell line sets
Platform:
GPL2507
Series:
GSE8686
36 Samples
Download data: TXT
DataSet
Accession:
GDS2987
ID:
2987

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

3.

Sentrix Human-6 Expression BeadChip

(Submitter supplied) The Sentrix Human-6 BeadChip can be used to study expression of over 47,000 human transcripts. Researchers can generate whole-genome expression profiles for 6 samples in parallel on a single BeadChip. Array is composed of 3 micron features with average feature redundancy of 30-fold . All features are QCed by sequential hybridizations process called array decoding. Probes are fully screened all-full-length 50-mers. more...
Organism:
Homo sapiens
7 DataSets
55 Series
1420 Samples
Download data: CSV
Platform
Accession:
GPL2507
ID:
100002507

4.

PASMC_atorvastatin_mevalonate_rep3

Organism:
Homo sapiens
Source name:
Human Pulmonary Artery Smooth Muscle Cells, atorvastatin and mevalonate treated 24 h
Platform:
GPL2507
Series:
GSE8686
Dataset:
GDS2987
Download data: TXT
Sample
Accession:
GSM215326
ID:
300215326

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db=gds|term=GSM215326[Accession]|query=18|qty=2|blobid=MCID_672b5831c619b038bd1ac358|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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