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Items: 3

1.

MNase titration reveals differences between nucleosome occupancy and chromatin accessibility

(Submitter supplied) Chromatin accessibility plays a fundamental role in gene regulation. One mechanism to regulate accessibility is nucleosome placement, which is often measured by quantifying protection of DNA from enzymatic digestion. We introduce a metric that uses micrococcal nuclease (MNase) digestion in a novel manner to measure chromatin accessibility by combining information from several digests of increasing depths. more...
Organism:
Homo sapiens; Mus musculus; Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL16791 GPL17275 GPL17021
74 Samples
Download data: BEDGRAPH
Series
Accession:
GSE78984
ID:
200078984
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

ESC1 whole chromatin rep1 16U MNase

Organism:
Mus musculus
Source name:
J1 ESC
Platform:
GPL17021
Series:
GSE78984
Download data: BEDGRAPH
Sample
Accession:
GSM2083107
ID:
302083107
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